Dosimetry of 177Lu-PSMA-617 after Mannitol Infusion and Glutamate Tablet Administration: Preliminary Results of EUDRACT/RSO 2016-002732-32 IRST Protocol

A Sarnelli, ML Belli, V Di Iorio, E Mezzenga, M Celli… - Molecules, 2019 - mdpi.com
Radio-ligand therapy (RLT) with177Lu-PSMA-617 is a promising option for patients with
metastatic castration-resistant prostate-cancer (mCRPC). A prospective phase-II study …

Single Center Experience with a 4-Week 177Lu-PSMA-617 Treatment Interval in Patients with Metastatic Castration-Resistant Prostate Cancer

J Kemppainen, A Kangasmäki, S Malaspina, B Pape… - Cancers, 2022 - mdpi.com
Simple Summary The optimal treatment regimen with 177Lu-PSMA-617 for metastatic
castration-resistant prostate cancer patients is not known. In this retrospective analysis, the …

Health-related quality of life and pain outcomes with [177Lu] Lu-PSMA-617 plus standard of care versus standard of care in patients with metastatic castration-resistant …

K Fizazi, K Herrmann, BJ Krause, K Rahbar… - The Lancet …, 2023 - thelancet.com
Background In VISION, the prostate-specific membrane antigen (PSMA)-targeted
radioligand therapy lutetium-177 [177 Lu] Lu-PSMA-617 (vipivotide tetraxetan) improved …

Intermittent Radioligand Therapy with 177Lu-PSMA-617 for Oligometastatic Castration-Resistant Prostate Cancer

N Mader, C Schoeler, N Pezeshkpour, K Klimek… - Cancers, 2023 - mdpi.com
Simple Summary Radioligand therapy (RLT) usually consists of predefined cycles of 177Lu-
PSMA-617 every 6–8 weeks. Although side-effects of RLT are considered well tolerable …

177Lu-PSMA Therapy in Metastatic Castration-Resistant Prostate Cancer

Y Sanli, DH Simsek, O Sanli, RM Subramaniam… - Biomedicines, 2021 - mdpi.com
The aim of this narrative review is to evaluate the current status of 177Lu-PSMA (prostate
specific membrane antigen) therapy for metastatic castration-resistant prostate cancer …

Efficacy and safety of Ac-225 PSMA radio ligand therapy in metastatic prostate cancer. A systematic review and metanalysis

GK Parida, RA Panda, K Bishnoi, K Agrawal - Med Princ Pract, 2023 - karger.com
Abstract Background: Actinium-225 (Ac-225) labelled PSMA RLT has been tested recently in
metastatic castration-resistant prostate cancer (mCRPC), with encouraging results. Ac-225 …

225Ac-PSMA-617 for therapy of prostate cancer

C Kratochwil, U Haberkorn, FL Giesel - Seminars in nuclear medicine, 2020 - Elsevier
Prostate-specific membrane antigen (PSMA)-targeting radio-ligand therapy with beta-
emitting 177 Lutetium has already been investigated in several early phase dosimetry …

177Lu-PSMA-617 versus docetaxel in chemotherapy-naïve metastatic castration-resistant prostate cancer: a randomized, controlled, phase 2 non-inferiority trial

S Satapathy, BR Mittal, A Sood, CK Das… - European Journal of …, 2022 - Springer
Purpose Lutetium-177 prostate-specific membrane antigen-617 (177 Lu-PSMA-617) in end-
stage metastatic castration-resistant prostate cancer (mCRPC) has reported favourable …

External radiation exposure, excretion, and effective half-life in 177Lu-PSMA-targeted therapies

J Kurth, BJ Krause, SM Schwarzenböck, L Stegger… - EJNMMI research, 2018 - Springer
Background Prostate-specific membrane antigen (PSMA)-targeted therapy with 177 Lu-
PSMA-617 is a therapeutic option for patients with metastatic castration-resistant prostate …

Where to next for theranostics in prostate cancer?

DG Murphy, N Sathianathen… - European …, 2019 - euoncology.europeanurology.com
The role of molecular imaging using small-molecule ligands labelled with 68Ga or 18F that
bind to prostate-specific membrane antigen (PSMA) continues to be defined for men …