Epidermal growth factor (EGF), a ligand of the EGF receptor, plays a critical role in the
development of gastric cancer. Genetic variants in its promoter region may influence …

The etiology of gastric cancer is not well-understood. Epidermal growth factor (EGF)
transduces growth signals to mitogen-activated protein kinase via RAS and BRAF, and …

Objective: Epidermal growth factor (EGF) has many biological functions and plays an
important role in the progression of various tumors including gastric cancer. An AG single …

The epidermal growth factor (EGF) pathway stimulates proliferation and differentiation of
epidermal and epithelial tissues, and plays an important role in tumorigenesis. The …

AIM: To investigate the association between epidermal growth factor (EGF)+ 61A/G
polymorphism and susceptibility to gastric cancer, through a cross-sectional study …

EGF promoter polymorphisms are observed to modulate EGF levels and thought to have
effect on susceptibility to various carcinomas but the results are inconsistent. In this meta …

Results The A allele of EGF+ 61 G/A was less frequently in gastric cancer patients than in
controls (OR= 0.73, 95% CI= 0.55-0.95, p= 0.02). The A allele frequency was also …

Genetic factors are known to be important in the development of esophageal squamous cell
carcinoma (ESCC). Epidermal growth factor (EGF) can activate several signaling pathways …

Background Epidermal growth factor (EGF) plays a pivotal role in cell proliferation,
differentiation, and tumorigenesis of epithelial tissues. Variation of the EGF+ 61A/G …

Epidermal growth factor (EGF) plays an important role in tumorigenesis. The association
between the+ 61 A/G polymorphism of the EGF gene and colon cancer risk remains …