[HTML][HTML] Association among polymorphisms in EGFR gene exons, lifestyle and risk of gastric cancer with gender differences in Chinese Han subjects

J Zhang, Z Zhan, J Wu, C Zhang, Y Yang, S Tong… - PLoS …, 2013 - journals.plos.org
Background The epidermal growth factor receptor (EGFR) gene plays a key role in tumor
survival, invasion, angiogenesis, and metastatic spread. Recent studies showed that gastric …

[HTML][HTML] Genetic variants in epidermal growth factor receptor pathway genes and risk of esophageal squamous cell carcinoma and gastric cancer in a Chinese …

WQ Li, N Hu, Z Wang, K Yu, H Su, L Wang, C Wang… - PLoS …, 2013 - journals.plos.org
The epidermal growth factor receptor (EGFR) signaling pathway regulates cell proliferation,
differentiation, and survival, and is frequently dysregulated in esophageal and gastric …

EGF+ 61A> G polymorphism and gastrointestinal cancer risk: a HuGE review and meta-analysis

Y Piao, Z Liu, Z Ding, L Xu, F Guo, Q Sun, X Xie - Gene, 2013 - Elsevier
Emerging evidences from preclinical and clinical studies have shown that epidermal growth
factor (EGF) has some effectiveness against endogenously arising carcinogenesis …

[PDF][PDF] Analysis of the polymorphisms EGFR-r521K and ERBB2-I655V in Mexican patients with gastric cancer and premalignant gastric lesions

JH Torres-Jasso, AR Bustos-Carpinteyro, ME Marín… - Rev Invest …, 2013 - academia.edu
The proto-oncogenes epidermal growth factor receptor (EGFR) and erythroblastic leukemia
viral oncogene homolog 2 (ERBB2), are involved in the development of diverse malignant …

Genetic polymorphism of epidermal growth factor 61A> G and cancer risk: a meta-analysis

YM Zhang, C Cao, K Liang - Cancer epidemiology, 2010 - Elsevier
Background: Numerous studies have investigated the risk of cancer associated with the
polymorphism of epidermal growth factor (EGF) 61A> G, but the results have been …

[PDF][PDF] EGFR gene polymorphisms-216G> T and-191C> A are risk markers for gastric cancer in Mexican population

JH Torres-Jasso, ME Marín… - Genetics and …, 2015 - geneticsmr.com
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with tyrosine-
kinase activity that plays an important role in multiple cellular functions. EGFR …

An Insertion/Deletion Polymorphism Within the Proximal Promoter of EGLN2 Is Associated With Susceptibility for Gastric Cancer in the Chinese Population

J Wang, J Zhang, C Zhou, L Chen… - Genetic Testing and …, 2014 - liebertpub.com
Gastric cancer (GC) is among the most common human malignancies and the second
leading cause of cancer-related death worldwide. Accumulated evidence from molecular …

A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcome

M Lanuti, G Liu, JM Goodwin, R Zhai, BC Fuchs… - Clinical Cancer …, 2008 - AACR
Purpose: The epidermal growth factor (EGF) pathway is important in esophageal
adenocarcinoma (EAC) tumorigenesis. We hypothesized that the EGF A61G homozygous …

A functional polymorphism in the epidermal growth factor gene is associated with risk for glioma in a Chinese population

Y Li, Y Zhao, J Liu, P Liu, Y Xu - Genetic Testing and Molecular …, 2012 - liebertpub.com
Epidermal growth factor (EGF) plays a key role in survival of neural and glial precursor cells.
A single nucleotide polymorphism of the EGF gene+ 61G/A in the 5'-untranslated region has …

Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer

KLG Spindler, JN Nielsen, D Ornskov… - Acta …, 2007 - Taylor & Francis
Introduction. EGF/EGFR interactions are important mechanisms behind colorectal tumour
development and growth. Recently a single nucleotide polymorphism in the EGF gene has …