Background: The epidermal growth factor receptor (EGFR) regulates important cellular
processes and is frequently implicated in human tumors. Three EGFR polymorphisms have …

Epidermal growth factor (EGF) plays an important role in cancer. A functional single
nucleotide polymorphism (SNP) in the 5′-untranslated region of the EGF gene (+ 61 A> G) …

Growth factors are important mediators of proliferation. Deregulation in growth factor
mechanisms as well as in its receptors will contribute to cancer development. One of the …

Epidermal growth factor receptor (EGFR) expression and gene copy number have been
observed to be associated with a positive clinical response to EGFR inhibitors. The present …

Background: Chronic hepatitis B virus (HBV) infection is a risk factor of hepatocellular
carcinoma (HCC) in China. Epidermal growth factor (EGF) plays an important role in …

A single nucleotide polymorphism (SNP) of the epidermal growth factor (EGF) gene+ 61 A/G
in the 5′-untranslated region has been reported to be associated with susceptibility to …

Background Gliomas account for almost 80% of primary malignant brain tumors. Epidermal
growth factor (EGF) is an interesting research candidate in which to look for genetic …

Abstract Background Polymorphisms in Epidermal Growth Factor Receptor (EGFR) gene
may influence EGFR production and/or activity, thereby modulating susceptibility to lung …

Background and objective: The epidermal growth factor receptor (EGFR) plays a major role
in cell proliferation of epithelial tissues, and its alterations frequently contribute to …

Aim: The aim of this study was to address the association of the EGF gene+ 61A/G
polymorphisms and HCC susceptibility in an Iranian population. Background: The …