Purpose: Epidermal growth factor (EGF) plays a critical role in cancer. A polymorphism in the
EGF gene (EGF+ 61) may influence its expression and contribute to cancer predisposition …

Numerous candidate genes have been proposed as susceptibility factors for the
development of nasopharyngeal carcinoma (NPC). Epidermal growth factor (EGF) and …

The goal of this study was to consolidate information on genetic risk factors for gastric
cancer. An additional aim was to investigate the influence of race on these genetic risk …

Background: The Chinese Hui ethnic group has diverse origins, including Arab, Persian,
Central Asian, and Mongol. The standardized mortality rate of gastric cancer in the Hui …

Context Overexpression of epidermal growth factor (EGF) in the liver induces transformation
to hepatocellular carcinoma in animal models. Polymorphisms in the EGF gene modulate …

Background Hepatocarcinogenesis is a complex process that may be influenced by many
factors, including polymorphism in the epidermal growth factor (EGF) gene. Previous work …

The EGFR signaling pathway is involved in carcinogenesis at multiple sites, particularly
colorectal cancer, and is a target of colorectal cancer chemotherapy. EGFR signaling is …

Background:: Epidermal growth factor receptor (EGFR) overexpression is associated with
poor prognosis in head and neck cancer. The first intron of EGFR gene is polymorphic (9–23 …

The incidence of breast cancer has steadily increased with an estimated 1 million new
diagnoses and 400,000 deaths per year worldwide (1). Only a small fraction of breast cancer …

Frequent mutations and loss of expression of E-cadherin have been reported in a number of
cancers. E-cadherin germ line mutations lead to a high risk of familial diffused gastric …