Neuroimaging studies have uncovered structural and functional alterations in the cingulate
cortex in individuals with autism spectrum disorders (ASD). Such abnormalities may underlie …

The pathophysiology of autism spectrum disorder (ASD) is not fully understood. We used
proton magnetic resonance spectroscopy to investigate metabolite concentration ratios in …

Background Despite rising prevalence of autism spectrum disorder (ASD), its brain bases
remain uncertain. Abnormal levels of N-acetyl compounds, glutamate+ glutamine, creatine+ …

BACKGROUND: Although several previous studies have been conducted, the neural basis
of autism spectrum disorder (ASD) is poorly understood. The objective of the present study …

Purpose Recently, neuroimaging studies were performed using 1H-magnetic resonance
spectroscopy (1H-MRS), revealing a quantitative alteration of neurochemicals (such as …

Over the last few years, awareness of autism spectrum disorder (ASD) in adults has
increased. The precise etiology of ASD is still unresolved. Animal research, genetic and …

BACKGROUND: Autism is a developmental disorder of unknown neurologic basis. Based
on prior work, we used proton magnetic resonance spectroscopic imaging (1H-MRSI) to …

This study assessed metabolic functioning of regional brain areas to address whether there
is a neurometabolic profile reflecting the underlying neuropathology in individuals with …

BACKGROUND: Although brain imaging studies have reported neurobiological
abnormalities in autism, the nature and distribution of the underlying neurochemical …

The nature of neurochemical changes in autism spectrum disorder (ASD) remains
controversial. We compared medial prefrontal cortex (mPFC) neurochemistry of twenty high …