In vitro assessment of the biocompatibility of chemically treated silicone materials with human lens epithelial cells

ECY Kao, J Seo, DJ McCanna, LN Subbaraman… - Scientific reports, 2022 - nature.com
Cytotoxicity testing is a regulatory requirement for safety testing of new ocular implants. In
vitro toxicity tests determine whether toxic chemicals are present on a material surface or …

Experimental study of new material for biocompatibility as orbital implant

RB Kormann, H Moreira, G Crescente… - Arquivos Brasileiros de …, 2013 - SciELO Brasil
OBJETIVO: Avaliar a biocompatibilidade de material FullCure 720®, que é uma resina, na
confecção de implante orbitário. Avaliou-se a resposta clínica dos animais, toxicidade …

The development of in vitro biocompatibility tests for the evaluation of intraocular biomaterials

AW Lloyd, S Dropcova, RGA Faragher, PR Gard… - Journal of Materials …, 1999 - Springer
Recent developments in ocular implant technology require the in vitro evaluation of ocular
compatibility in early stage development programs. This requires an understanding and …

[PDF][PDF] Soft-tissue response to synthetic polymer implants made of cross-linked polyurethane and containing a biologically active substance, albucid or dacarbazine, in …

NA Galatenko, DV Kulyesh, AP Maletskyi… - Journal of …, 2018 - ozhurnal.com
Background: It is an urgent task of the today's science to search for and introduce
biointegrable synthetic materials into medical practice. Purpose: To investigate the soft …

Evaluation of iris color stability in ocular prosthesis

RC Reis, RB Dias, JCM Carvalho - Brazilian Dental Journal, 2008 - SciELO Brasil
Accurate iris reproduction in the fabrication of ocular prosthesis in order to match the
remaining eye is a key factor to mask the loss and achieve an esthetic outcome for …

In vitro methods of assessing ocular biocompatibility using THP-1-derived macrophages

DJ McCanna, AV Barthod-Malat… - Cutaneous and Ocular …, 2015 - Taylor & Francis
Macrophages play an important role in the elimination of infections, the removal of debris
and in tissue repair after infection and trauma. In vitro models that assess ocular …

Comparison of toxicological profiles of benzalkonium chloride and polyquaternium-1: an experimental study

A Labbé, A Pauly, H Liang… - Journal of Ocular …, 2006 - liebertpub.com
Purpose: The aim of this study was to compare, in vivo on a rat model, two different
preservatives—benzalkonium chloride (BAC) and polyquaternium-1 (PQ-1)—using new …

Cytotoxicity of contact lens multipurpose solutions: role of oxidative stress, mitochondrial activity and P2X7 cell death receptor activation

M Dutot, JM Warnet, C Baudouin, P Rat - european journal of …, 2008 - Elsevier
OBJECTIVE: To investigate the cytotoxicity of multipurpose solutions used for contact lens
disinfection. METHODS: Four multipurpose solutions (Optifree® containing quaternary …

[HTML][HTML] In vitro ultraviolet–induced damage in human corneal, lens, and retinal pigment epithelial cells

HY Youn, DJ McCanna, JG Sivak, LW Jones - Molecular vision, 2011 - ncbi.nlm.nih.gov
Purpose The purpose was to develop suitable in vitro methods to detect ocular epithelial cell
damage when exposed to UV radiation, in an effort to evaluate UV-absorbing ophthalmic …

Tissue reaction after silicone and poly (methyl methacrylate) intraocular lens implantation: a light and electron microscopy study in a rabbit model

W Kulnig, R Menapace, C Skorpik, M Juchem - Journal of Cataract & …, 1989 - Elsevier
We describe the histopathologic results of extracapsular lens extraction and silicone and
poly (methyl methacrylate)(PMMA) intraocular lens (IOL) implantation in 36 rabbit eyes …