Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does …

V Rusch, D Klimstra, E Venkatraman, PW Pisters… - Clinical cancer research …, 1997 - AACR
The epidermal growth factor receptor (EGFR) and its ligand transforming growth factor (TGF)
alpha are hypothesized to form an autocrine growth loop in non-small cell lung cancer …

Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung

V Rusch, J Baselga, C Cordon-Cardo, J Orazem… - Cancer research, 1993 - AACR
The epidermal growth factor receptor (EGFR) and one of its ligands, transforming growth
factor α (TGF-α), are thought to function as a potential autocrine loop in non-small cell lung …

Expression of EGF, TGF-alpha and EGFR in squamous cell lung carcinomas.

V Gorgoulis, D Aninos, P Mikou, P Kanavaros… - Anticancer …, 1992 - europepmc.org
Immunohistochemical study of epidermal growth factor (EGF), epidermal growth factor
receptor (EGFR) and transforming growth factor-alpha (TGF-alpha) expression was …

Expression of epidermal growth factor receptor (EGF-R) in non-small cell lung cancer. Use of archival tissue and correlation of EGF-R with histology, tumour size, node …

H Dazzi, PS Hasleton, N Thatcher, DM Barnes… - British journal of …, 1989 - nature.com
A total of 152 non-small cell lung cancers (NSCLC) were studied retrospectively to
determine the relationship between epidermal growth factor receptor (EGF-R) status and the …

Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas: an immunohistochemical and fluorescence in situ …

S Suzuki, Y Dobashi, H Sakurai… - … Journal of the …, 2005 - Wiley Online Library
BACKGROUND Recently, molecular therapies targeting epidermal growth factor receptor
(EGFR) have been developed for clinical use. The current study was conducted to determine …

Phosphorylation, but not overexpression, of epidermal growth factor receptor is associated with poor prognosis of non-small cell lung cancer patients.

T Kanematsu, S Yano, H Uehara, Y Bando… - Oncology …, 2003 - europepmc.org
Epidermal growth factor receptor (EGFR) is commonly overexpressed in non-small cell lung
cancer (NSCLC) and its tyrosine kinase phosphorylation is thought to be an ideal target in …

Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas: Comparison of four commercially available …

HJ Lee, X Xu, G Choe, DH Chung, JW Seo, JH Lee… - Lung Cancer, 2010 - Elsevier
Epidermal growth factor receptor (EGFR) overexpression in nonsmall cell lung carcinomas
(NSCLC) is variable ranging from 19% to 89% and its prognostic value remains …

Evidence for a role of EGF receptor in the progression of human lung carcinoma.

K Pavelic, Z Banjac, J Pavelic, S Spaventi - Anticancer research, 1993 - europepmc.org
Sixty-three primary lung carcinomas were examined immunohistochemically for the
presence of epidermal growth factor receptors (EGF-R). Of these tumors 35 (55.5%) were …

Epidermal growth factor receptors in non-small cell lung cancer

D Veale, T Ashcroft, C Marsh, GJ Gibson… - British journal of …, 1987 - nature.com
The epidermal growth factor receptor is homologous to the oncogene erb-beta and is the
receptor for a class of tumour growth factors (TGF-alpha). The clinical correlations with its …

A comparison of epidermal growth factor receptor levels and other prognostic parameters in non-small cell lung cancer

S Fujino, T Enokibori, N Tezuka, Y Asada… - European Journal of …, 1996 - Elsevier
Epidermal growth factor receptor (EGFR) was measured using a competitive radioligand
binding assay in membrane preparations from 74 primary human non-small cell lung cancer …