The ascending dopamine system of the mammalian brain has been associated with motor,
mnemonic and goaldirected or reward-related behaviour. The most progress in …

Dopamine has been implicated in the modulation of working memory via its interactions with
circuits located in the prefrontal cortex of rodents and non-human primates. However, the …

Dopamine (DA) plays a critical role in cognition, motivation and information processing. DA
action has been shown to both improve and/or impair cognition across different receptor …

Studies of human subjects performing cognitive tasks on and off dopaminergic drugs have
suggested a specific role of dopamine in cognitive processes, particularly in working …

Along with dementia, Parkinson's disease (PD) is associated with subtle but widespread
cognitive impairment even in the absence of clinically apparent cognitive decline. Many of …

Although dopamine has been closely associated with prefrontal function, and with working
memory in monkeys, the effects of dopamine agonists on human cognitive performance are …

There is now substantial evidence from animal studies showing modulation of cognitive
performance after administration of dopaminergic agents. Previous studies have focused on …

Converging evidence suggests that dopaminergic projections to the prefrontal cortex (PFC)
modulate both attention and working memory processes that may be related to either …

Although dopamine D3 receptor antagonists have been shown to enhance frontocortical
cholinergic transmission and improve cognitive performance in rodents, data are limited and …

PHARMACOLOGICAL manipulation of brain dopamine concentration affects visuospatial
working memory in humans and in animals, the latter effects localized to the prefrontal …