Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy
Current cancer immunotherapy has limited response rates in a large variety of solid tumors
partly due to the low immunogenicity of the tumor cells and the immunosuppressive tumor …
partly due to the low immunogenicity of the tumor cells and the immunosuppressive tumor …
Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency
Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
Cancer nanomedicine meets immunotherapy: opportunities and challenges
Q Sun, X Bai, AM Sofias, R van der Meel… - Acta Pharmacologica …, 2020 - nature.com
Cancer nanomedicines have shown promise in combination immunotherapy, thus far mostly
preclinically but also already in clinical trials. Combining nanomedicines with …
preclinically but also already in clinical trials. Combining nanomedicines with …
Stimuli‐responsive nanodelivery systems for amplifying immunogenic cell death in cancer immunotherapy
W Xu, W Liu, J Yang, J Lu, H Zhang… - Immunological …, 2024 - Wiley Online Library
Immunogenic cell death (ICD) is a special pattern of tumor cell death, enabling to elicit tumor‐
specific immune response via the release of damage‐associated molecular patterns and …
specific immune response via the release of damage‐associated molecular patterns and …
Recent progress in stimuli-responsive nanosystems for inducing immunogenic cell death
Low immunogenicity and immunosuppressive tumor microenvironments are major hurdles
in the application of cancer immunotherapy. To date, several immunogenic cell death (ICD) …
in the application of cancer immunotherapy. To date, several immunogenic cell death (ICD) …
Applying nanotechnology to boost cancer immunotherapy by promoting immunogenic cell death
L Fu, X Ma, Y Liu, Z Xu, Z Sun - Chinese Chemical Letters, 2022 - Elsevier
Tumor immunotherapy, especially immune checkpoint blockade (ICB), has revolutionized
the cancer field. However, the limited response of tumors to immunotherapy is a major …
the cancer field. However, the limited response of tumors to immunotherapy is a major …
[HTML][HTML] Symphony of nanomaterials and immunotherapy based on the cancer–immunity cycle
Q Li, Z Shi, F Zhang, W Zeng, D Zhu, L Mei - Acta Pharmaceutica Sinica B, 2022 - Elsevier
The immune system is involved in the initiation and progression of cancer. Research on
cancer and immunity has contributed to the development of several clinically successful …
cancer and immunity has contributed to the development of several clinically successful …
Nano delivery of chemotherapeutic ICD inducers for tumor immunotherapy
Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …
confirmed to activate the host immune system to prevent, control, and eliminate tumors …
[HTML][HTML] Nanomedicines modulating tumor immunosuppressive cells to enhance cancer immunotherapy
Y Zhu, X Yu, SD Thamphiwatana, Y Zheng… - … Pharmaceutica Sinica B, 2020 - Elsevier
Cancer immunotherapy has veered the paradigm of cancer treatment. Despite recent
advances in immunotherapy for improved antitumor efficacy, the complicated tumor …
advances in immunotherapy for improved antitumor efficacy, the complicated tumor …
Multifunctional Nano‐Biomaterials for Cancer Therapy via Inducing Enhanced Immunogenic Cell Death
Immunotherapy is considered to be one of the most promising methods to overcome cancer.
Immunogenic cell death (ICD), as a special form of cell death that can trigger an antitumor …
Immunogenic cell death (ICD), as a special form of cell death that can trigger an antitumor …
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