Acute circulatory failure associated with infection, referred to as septic shock, is
characterized by an inadequate tissue perfusion and oxygenation relative to metabolic …

A growing body of evidence exists associating depressed microcirculatory function and
morbidity and mortality in a wide array of clinical scenarios. It has been suggested that …

Purpose The clinical use of vasoactive drugs is not only intended to improve systemic
hemodynamic variables, but ultimately to attenuate derangements in organ perfusion and …

Efforts to improve survival from sepsis are focusing increasingly on intervention during the
earliest stages of this disease. The importance of derangements in microvascular flow in …

After shock, persistent oxygen extraction deficit despite the apparent adequate recovery of
systemic hemodynamic and oxygen-derived variables has been a source of uncertainty and …

Cardiogenic shock is usually defined as primary cardiac dysfunction with low cardiac output
leading to critical organ hypoperfusion, and tissue hypoxia, resulting in high mortality rate …

Severe sepsis is defined by organ failure, often of the kidneys, heart, and brain. It has been
proposed that inadequate delivery of oxygen, or insufficient extraction of oxygen in tissue …

Objective Sepsis mortality is closely linked to multi-organ failure, and impaired
microcirculatory blood flow is thought to be pivotal in the pathogenesis of sepsis-induced …

Microcirculatory hemodynamics have to be restored as soon as possible during the early
phase of the management of acutely unwell patients. Future trials should test whether …

Microcirculation is a particular organ of the cardiovascular system. The goal of this narrative
review is a critical reappraisal of the present knowledge of microcirculation monitoring …