Research progresses of molecular mechanism of pyroptosis and its related diseases

W Gong, Y Shi, J Ren - Immunobiology, 2020 - Elsevier
Pyroptosis is a newly discovered untypical form of programmed cell death by inflammatory
response, which is dependent on the classic pathway of Caspase-1 and the non-canonical …

[HTML][HTML] Molecular characteristics of cell pyroptosis and its inhibitors: a review of activation, regulation, and inhibitors

S Wei, M Feng, S Zhang - International Journal of Molecular Sciences, 2022 - mdpi.com
Pyroptosis is an active and ordered form of programmed cell death. The signaling pathways
of pyroptosis are mainly divided into canonical pathways mediated by caspase-1 and …

[HTML][HTML] The role of pyroptosis in inflammatory diseases

R Chai, Y Li, L Shui, L Ni, A Zhang - Frontiers in Cell and …, 2023 - frontiersin.org
Programmed cell death has crucial roles in the physiological maturation of an organism, the
maintenance of metabolism, and disease progression. Pyroptosis, a form of programmed …

Pyroptosis as a double-edged sword: The pathogenic and therapeutic roles in inflammatory diseases and cancers

Z Liu, C Wang, C Lin - Life Sciences, 2023 - Elsevier
Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …

[HTML][HTML] Research progress of the relationship between pyroptosis and disease

Y Ma, J Jiang, Y Gao, T Shi, X Zhu… - American journal of …, 2018 - ncbi.nlm.nih.gov
Pyroptosis, characterized by proinflammation, has been defined as a new type of
programmed cell death in recent years. Inflammasomes are activated by the corresponding …

Pyroptosis in health and disease

G Imre - American Journal of Physiology-Cell Physiology, 2024 - journals.physiology.org
The field of cell death has witnessed significant advancements since the initial discovery of
apoptosis in the 1970s. This review delves into the intricacies of pyroptosis, a more recently …

[HTML][HTML] Pyroptosis: a new paradigm of cell death for fighting against cancer

Y Tan, Q Chen, X Li, Z Zeng, W Xiong, G Li, X Li… - Journal of Experimental …, 2021 - Springer
Background Unraveling the mystery of cell death is one of the most fundamental progresses
of life sciences during the past decades. Regulated cell death (RCD) or programmed cell …

Progress in the study of molecular mechanisms of cell pyroptosis in tumor therapy

D Wang, X Wan - International Immunopharmacology, 2023 - Elsevier
Pyroptosis, also known as cellular inflammatory necrosis, is a programmed cell death
mediated by the Gasdermin family of proteins. The mechanisms by which pyroptosis occurs …

[HTML][HTML] Molecular mechanisms of pyroptosis and its role in anti-tumor immunity

H Huang, Y Weng, W Tian, X Lin, J Chen… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Pyroptosis is a form of cell death that is characterized by the destruction of the cell, and it has
implications in both the immune system and cancer immunotherapy. The gasdermin family is …

Role of pyroptosis in liver diseases

A Al Mamun, Y Wu, C Jia, F Munir, KJ Sathy… - International …, 2020 - Elsevier
Pyroptosis is known as a novel form of pro-inflammatory cell death program, which is
exceptional from other types of cell death programs. Particularly, pyroptosis is characterized …