A perspective on roles played by innate and adaptive immunity in the pathobiology of neurodegenerative disorders
HE Gendelman, RL Mosley - Journal of Neuroimmune Pharmacology, 2015 - Springer
Aberrant innate and adaptive immune responses are neurodegenerative disease effectors.
Disease is heralded by a generalized, but subtle immune activation orchestrated by the …
Disease is heralded by a generalized, but subtle immune activation orchestrated by the …
[HTML][HTML] Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders
KM Anderson, KE Olson, KA Estes, K Flanagan… - Translational …, 2014 - Springer
Inappropriate T cell responses in the central nervous system (CNS) affect the pathogenesis
of a broad range of neuroinflammatory and neurodegenerative disorders that include, but …
of a broad range of neuroinflammatory and neurodegenerative disorders that include, but …
Neurodegenerative diseases: The immunological perspective
M Molteni, C Rossetti - Journal of neuroimmunology, 2017 - Elsevier
Increasing evidence supports the notion that the neurodegenerative process occurring in
Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis …
Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis …
Adaptive immunity in neurodegenerative and neuropsychological disorders
R Lee Mosley - Journal of neuroimmune pharmacology, 2015 - Springer
Neurodegenerative and neuropsychological disorders are becoming a greater proportion of
the global disease burden; however the pathogenic mechanisms by which these disorders …
the global disease burden; however the pathogenic mechanisms by which these disorders …
The innate and adaptive immunological aspects in neurodegenerative diseases
MCO Rodrigues, PR Sanberg, LE Cruz… - Journal of …, 2014 - Elsevier
Neurodegenerative diseases affect a considerable percentage of the elderly population.
New therapeutic approaches are warranted, aiming to at least delay and possibly reverse …
New therapeutic approaches are warranted, aiming to at least delay and possibly reverse …
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
KR Doty, MV Guillot-Sestier, T Town - Brain research, 2015 - Elsevier
Neurodegenerative diseases share common features, including catastrophic neuronal loss
that leads to cognitive or motor dysfunction. Neuronal injury occurs in an inflammatory milieu …
that leads to cognitive or motor dysfunction. Neuronal injury occurs in an inflammatory milieu …
[HTML][HTML] Immunological aspects of central neurodegeneration
M Niso-Santano, JM Fuentes, L Galluzzi - Cell Discovery, 2024 - nature.com
The etiology of various neurodegenerative disorders that mainly affect the central nervous
system including (but not limited to) Alzheimer's disease, Parkinson's disease and …
system including (but not limited to) Alzheimer's disease, Parkinson's disease and …
Innate immunity and neurodegeneration
The innate immune system plays diverse roles in health and disease. It represents the first
line of defense against infection and is involved in tissue repair, wound healing, and …
line of defense against infection and is involved in tissue repair, wound healing, and …
Inflammation in neurodegenerative diseases
S Amor, F Puentes, D Baker, P Van Der Valk - Immunology, 2010 - Wiley Online Library
Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in
the central nervous system, is the primary pathological feature of acute and chronic …
the central nervous system, is the primary pathological feature of acute and chronic …
Boosting T-cell immunity as a therapeutic approach for neurodegenerative conditions: the role of innate immunity
M Schwartz, A London, R Shechter - Neuroscience, 2009 - Elsevier
Our research group has been working for more than a decade on the cross-talk between the
immune and the nervous systems. Due to the unique nature of the central nervous system …
immune and the nervous systems. Due to the unique nature of the central nervous system …