Quantitative determination of potent α-glucosidase inhibitors, salacinol and kotalanol, in Salacia species using liquid chromatography–mass spectrometry

O Muraoka, T Morikawa, S Miyake, J Akaki… - … of pharmaceutical and …, 2010 - Elsevier
A practical HPLC–MS method for the quantitative determination of salacinol (1) and
kotalanol (2), potent α-glucosidase inhibitors from Salacia species (Hippocrateaceae) as a …

Kotalanol, a potent α-glucosidase inhibitor with thiosugar sulfonium sulfate structure, from antidiabetic Ayurvedic medicine Salacia reticulata

M Yoshikawa, T Murakami, K Yashiro… - Chemical and …, 1998 - jstage.jst.go.jp
抄録 A potent natural α-glucosidase inhibitor called kotalanol has been isolated from an
antidiabetic traditional Ayurvedic medicine, the roots and stems of Salacia reticulata WIGHT …

Safety evaluation of an extract from Salacia oblonga

BW Wolf, SE Weisbrode - Food and chemical toxicology, 2003 - Elsevier
Plant extracts from the Salacia genus have been found to have intestinal α-glucosidase
inhibitor activity, which may have application to the development of medical foods for people …

[PDF][PDF] Salaprinol and ponkoranol with thiosugar sulfonium sulfate structure from Salacia prinoides and α-glucosidase inhibitory activity of ponkoranol and kotalanol …

M Yoshikawa, F Xu, S Nakamura, T Wang… - …, 2008 - triggered.edina.clockss.org
The methanolic extract from the roots and stems of Indian Salacia prinoides and its water-
eluted fraction of Diaion HP-20 column were found to exhibit inhibitory activities against α …

Three new triterpenoids from Salacia hainanensis Chun et How showed effective anti-α-glucosidase activity

J Huang, Z Guo, P Cheng, B Sun, HY Gao - Phytochemistry Letters, 2012 - Elsevier
To identify the chemical constituents with hypoglycemic activity in Salacia hainanensis Chun
et How, this study was carried out on the roots of S. hainanensis. By means of a bioassay …

Salacia reticulata Improves Serum Lipid Profiles and Glycemic Control in Patients with Prediabetes and Mild to Moderate Hyperlipidemia: A Double-Blind, Placebo …

HN Shivaprasad, M Bhanumathy, G Sushma… - Journal of Medicinal …, 2013 - liebertpub.com
The present randomized, double-blind, placebo-controlled study evaluated the efficacy and
safety of Salacia reticulata leaves and root bark extracts in 29 patients with prediabetes and …

Anti-diabetic activity of a leaf extract prepared from Salacia reticulata in mice

K Yoshino, Y Miyauchi, T Kanetaka… - Bioscience …, 2009 - jstage.jst.go.jp
The effects of a water extract prepared from the leaves of Salacia reticulata on the
absorption of sugars in normal and type 1 diabetic mice were investigated. The …

Hypoglycemic Activity of the Root and Stem of Salacia reticulata. var. β-diandra. in Alloxan Diabetic Rats

N Ruvin Kumara, RN Pathirana… - Pharmaceutical …, 2005 - Taylor & Francis
The hypoglycemic activity of the aqueous extract of the root bark of Salacia reticulata.(known
as kotala himbatu.) has previously been confirmed in the normal healthy rat model. In this …

Evaluation of Salacia Species as Anti‐diabetic Natural Resources Based on Quantitative Analysis of Eight Sulphonium Constituents: A New Class of α‐Glucosidase …

J Akaki, T Morikawa, S Miyake… - Phytochemical …, 2014 - Wiley Online Library
Introduction Stems and roots of Salacia genus plants have been used in Ayurveda as a
specific remedy for early stage diabetes. Previous investigations identified four sulphonium …

Absolute stereostructure of potent α-glucosidase inhibitor, salacinol, with unique thiosugar sulfonium sulfate inner salt structure from Salacia reticulata

M Yoshikawa, T Morikawa, H Matsuda… - Bioorganic & medicinal …, 2002 - Elsevier
A most potent α-glucosidase inhibitor named salacinol has been isolated from an
antidiabetic Ayurvedic traditional medicine, Salacia reticulata WIGHT, through bioassay …