In a genomic era, placental pathology still holds the key in the nondysmorphic stillbirth

J Campbell, K Armstrong… - Pediatric and …, 2018 - journals.sagepub.com
Objective To explore the relative utility of genetic testing in contrast to placental pathology in
explaining causation of death in the structurally normal stillborn population. Methods A …

Quantitative assessment of placental morphology may identify specific causes of stillbirth

I Ptacek, A Smith, A Garrod, S Bullough, N Bradley… - BMC clinical …, 2016 - Springer
Background Stillbirth is frequently the result of pathological processes involving the
placenta. Understanding the significance of specific lesions is hindered by qualitative …

Stillbirth evaluation: a stepwise assessment of placental pathology and autopsy

ES Miller, L Minturn, R Linn, DE Weese-Mayer… - American journal of …, 2016 - Elsevier
Background The American Congress of Obstetricians and Gynecologists places special
emphasis on autopsy as one of the most important tests for evaluation of stillbirth. Despite a …

Placental pathology findings in unexplained pregnancy losses

BB Thompson, PH Holzer, HJ Kliman - Reproductive Sciences, 2024 - Springer
There are approximately 5 million pregnancies per year in the USA, with 1 million ending in
miscarriage (a loss occurring prior to 20 weeks of gestation) and over 20,000 ending in …

Genomics of stillbirth

JL Giordano, RJ Wapner - Seminars in Perinatology, 2023 - Elsevier
Stillbirth, defined as fetal death at 20 weeks gestation or later, is a devastating pregnancy
outcome affecting 1 in 175 pregnancies in the United States. Although efforts to understand …

Diagnostic utility of pathological investigations in late gestation stillbirth: a cohort study

SK Lou, S Keating, E Kolomietz… - Pediatric and …, 2020 - journals.sagepub.com
Objective Near term unexpected stillbirth is a common, complex diagnostic challenge. We
review a large cohort of near term to term gestation unexpected fetal deaths to document the …

Results of full postmortem examination in a cohort of clinically unexplained stillbirths: undetected fetal growth restriction and placental insufficiency are prevalent …

C Blythe, REZ Vazquez, MS Cabrera… - Journal of …, 2019 - nature.com
Objective To analyze a cohort of clinically unexplained stillbirths (CUS) referred for
postmortem. Study Design In total, 258 CUS were referred for full postmortem between 2009 …

Systematic review of placental pathology reported in association with stillbirth

I Ptacek, NJ Sebire, JA Man, P Brownbill, AEP Heazell - Placenta, 2014 - Elsevier
Introduction Histopathological examination of the placenta is recommended to determine the
cause of stillbirth. Although some reports find causal or contributory placental abnormalities …

Identifying causes and associated factors of stillbirths using autopsy of the fetus and placenta

E Kedar Sade, D Lantsberg, M Tagar Sar-el… - Archives of Gynecology …, 2024 - Springer
Purpose The study aimed to evaluate the causes of death and associated factors in cases of
stillbirth, using post-mortem examination and applying a rigorous, evidence-based holistic …

The placenta in stillbirth

TY Khong - Current Diagnostic Pathology, 2006 - Elsevier
Stillbirth is an absolute indication for pathological examination of the placenta. Placental
histopathology can shed light on the cause of the stillbirth and help in the management of …