Biological role of anaplastic lymphoma kinase in neuroblastoma
Y Osajima-Hakomori, I Miyake, M Ohira… - The American journal of …, 2005 - Elsevier
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase receptor originally identified as part
of the chimeric nucleophosmin-ALK protein in the t (2; 5) chromosomal rearrangement …
of the chimeric nucleophosmin-ALK protein in the t (2; 5) chromosomal rearrangement …
The role of anaplastic lymphoma kinase in pediatric cancers
J Takita - Cancer science, 2017 - Wiley Online Library
The anaplastic lymphoma kinase (ALK) gene was initially identified as a fusion partner of the
nucleophosmin gene in anaplastic large‐cell lymphoma with t (2; 5)(p23; q35) translocation …
nucleophosmin gene in anaplastic large‐cell lymphoma with t (2; 5)(p23; q35) translocation …
Aberrant activation of ALK kinase by a novel truncated form ALK protein in neuroblastoma
J Okubo, J Takita, Y Chen, K Oki, R Nishimura, M Kato… - Oncogene, 2012 - nature.com
Anaplastic lymphoma kinase (ALK) was originally identified from a rare subtype of non-
Hodgkin's lymphomas carrying t (2; 5)(p23; q35) translocation, where ALK was constitutively …
Hodgkin's lymphomas carrying t (2; 5)(p23; q35) translocation, where ALK was constitutively …
Biochemical detection of novel anaplastic lymphoma kinase proteins in tissue sections of anaplastic large cell lymphoma
K Pulford, B Falini, J Cordell, A Rosenwald, G Ott… - The American journal of …, 1999 - Elsevier
The (2; 5) translocation, found in many T-cell and null cell anaplastic large cell lymphomas
(ALCLs), creates a hybrid gene encoding the 80-kd NPM-ALK protein. Typically neoplastic …
(ALCLs), creates a hybrid gene encoding the 80-kd NPM-ALK protein. Typically neoplastic …
Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines
I Miyake, Y Hakomori, A Shinohara, T Gamou, M Saito… - Oncogene, 2002 - nature.com
Shc family of docking proteins, ShcA, ShcB and ShcC, play roles in cellular signal
transduction by binding to phosphotyrosine residues of various activated receptor tyrosine …
transduction by binding to phosphotyrosine residues of various activated receptor tyrosine …
Anaplastic lymphoma kinase proteins and malignancy
K Pulford, SW Morris, DY Mason - Current opinion in hematology, 2001 - journals.lww.com
The anaplastic lymphoma kinase (ALK) gene fuses to the nucleophosmin (NPM) gene as a
result of a (2; 5) translocation associated with a subtype of human lymphoma (initially …
result of a (2; 5) translocation associated with a subtype of human lymphoma (initially …
Expression of anaplastic lymphoma kinase in soft tissue tumors: an immunohistochemical and molecular study of 249 cases
XQ Li, M Hisaoka, DR Shi, XZ Zhu, H Hashimoto - Human pathology, 2004 - Elsevier
Although anaplastic lymphoma kinase (ALK) has been considered a diagnostic marker
specifying a subset of anaplastic large cell lymphomas and inflammatory myofibroblastic …
specifying a subset of anaplastic large cell lymphomas and inflammatory myofibroblastic …
Role of the subcellular localization of ALK tyrosine kinase domain in neuronal differentiation of PC12 cells
JY Gouzi, C Moog-Lutz, M Vigny… - Journal of cell …, 2005 - journals.biologists.com
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase essentially and transiently
expressed in specific areas of the developing central and peripheral nervous systems. We …
expressed in specific areas of the developing central and peripheral nervous systems. We …
Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage
J Mourali, A Bénard, FC Lourenço… - … and Cellular Biology, 2006 - Taylor & Francis
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase, initially discovered as part
of the NPM-ALK fusion protein, resulting from the t (2; 5) translocation that is frequently …
of the NPM-ALK fusion protein, resulting from the t (2; 5) translocation that is frequently …
Anaplastic lymphoma kinase proteins in growth control and cancer
K Pulford, SW Morris, F Turturro - Journal of cellular physiology, 2004 - Wiley Online Library
The normal functions of full‐length anaplastic lymphoma kinase (ALK) remain to be
completely elucidated. Although considered to be important in neural development, recent …
completely elucidated. Although considered to be important in neural development, recent …