Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like …
T Gotoh, T Sonoki, A Nagasaki, K Terada, M Takiguchi… - FEBS letters, 1996 - Elsevier
Arginase exists in two isoforms. Liver-type arginase (arginase I) is expressed almost
exclusively in the liver and catalyzes the last step of urea synthesis, whereas the nonhepatic …
exclusively in the liver and catalyzes the last step of urea synthesis, whereas the nonhepatic …
Chromosomal localization of the human arginase II gene and tissue distribution of its mRNA
T Gotoh, M Araki, M Mori - Biochemical and biophysical research …, 1997 - Elsevier
Liver-type arginase (arginase I) is expressed almost exclusively in the liver and catalyzes
the last step of urea synthesis, whereas the nonhepatic type (arginase II) is expressed in …
the last step of urea synthesis, whereas the nonhepatic type (arginase II) is expressed in …
Regulation of the urea cycle enzyme genes in nitric oxide synthesis
M Mori, T Gotoh, A Nagasaki, M Takiguchi… - Journal of inherited …, 1998 - Springer
Nitric oxide (NO) is synthesized from arginine by nitric-oxide synthase (NOS), and citrulline
that is generated can be recycled to arginine by argininosuccinate synthase (AS) and …
that is generated can be recycled to arginine by argininosuccinate synthase (AS) and …
Expression, purification, and characterization of human type II arginase
DM Colleluori, SM Morris Jr, DE Ash - Archives of Biochemistry and …, 2001 - Elsevier
Human type II arginase, which is extrahepatic and mitochondrial in location, catalyzes the
hydrolysis of arginine to form ornithine and urea. While type I arginases function in the net …
hydrolysis of arginine to form ornithine and urea. While type I arginases function in the net …
Distinct arginase isoforms expressed in primary and transformed macrophages: regulation by oxygen tension
CA Louis, JS Reichner, WL Henry Jr… - American Journal …, 1998 - journals.physiology.org
Experiments were performed to identify arginase isoforms expressed in primary and
transformed rodent macrophages and to determine the molecular mechanisms for the …
transformed rodent macrophages and to determine the molecular mechanisms for the …
Cloning and characterization of the human type II arginase gene
JG Vockley, CP Jenkinson, H Shukla, RM Kern… - Genomics, 1996 - Elsevier
There are two forms of arginase in humans, both catalyzing the hydrolysis of arginine to
ornithine and urea. Recent studies in animal models and in Type I arginase-deficient …
ornithine and urea. Recent studies in animal models and in Type I arginase-deficient …
Partial cloning and characterization of an arginine decarboxylase in the kidney
J Morrissey, R McCracken, S Ishidoya, S Klahr - Kidney international, 1995 - Elsevier
Partial cloning and characterization of an arginine decarboxylase in the kidney. Using
homology-based polymerase chain reaction (PCR) amplification, we demonstrate the …
homology-based polymerase chain reaction (PCR) amplification, we demonstrate the …
Regulation of the genes for arginase isoforms and related enzymes in mouse macrophages by lipopolysaccharide
Salimuddin, A Nagasaki, T Gotoh… - American Journal of …, 1999 - journals.physiology.org
Arginase exists in two isoforms, the hepatic (arginase I) and extrahepatic types (arginase II).
Arginase I is markedly induced in rat peritoneal macrophages and rat tissues in vivo by …
Arginase I is markedly induced in rat peritoneal macrophages and rat tissues in vivo by …
Immunohistochemical localization of arginase II and other enzymes of arginine metabolism in rat kidney and liver
K Miyanaka, T Gotoh, A Nagasaki, M Takeya… - The Histochemical …, 1998 - Springer
Arginine is a precursor for the synthesis of urea, polyamines, creatine phosphate, nitric oxide
and proteins. It is synthesized from ornithine by argininosuccinate synthetase and …
and proteins. It is synthesized from ornithine by argininosuccinate synthetase and …
Regulation of arginase isoforms I and II by IL-4 in cultured murine peritoneal macrophages
CA Louis, V Mody, WL Henry Jr… - American Journal …, 1999 - journals.physiology.org
Macrophages can express two arginase isoforms with distinct subcellular localization
(cytosolic AI and mitochondrial AII). These isoforms are products of different genes and are …
(cytosolic AI and mitochondrial AII). These isoforms are products of different genes and are …