Statin treatment and functional outcome after ischemic stroke: case–control and meta-analysis

A Biffi, WJ Devan, CD Anderson, L Cortellini, KL Furie… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Multiple studies suggest that statin use before acute ischemic
stroke is associated with improved functional outcome. However, available evidence is …

[HTML][HTML] Association between statin use and short-term outcome based on severity of ischemic stroke: a cohort study

B Song, Y Wang, X Zhao, L Liu, C Wang, A Wang… - PLoS …, 2014 - journals.plos.org
Background Statins reportedly improve clinical outcomes for ischemic stroke patients.
However, it is unclear whether the contribution of statin treatment varies depending on the …

Statin therapy and outcome after ischemic stroke: systematic review and meta-analysis of observational studies and randomized trials

D Ní Chróinín, K Asplund, S Åsberg, E Callaly… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Although experimental data suggest that statin therapy may
improve neurological outcome after acute cerebral ischemia, the results from clinical studies …

Effect of previous statin therapy on severity and outcome in ischemic stroke patients: a population-based study

C Aboa-Eboulé, C Binquet, A Jacquin, M Hervieu… - Journal of …, 2013 - Springer
Although statin therapy has been shown to be effective in the prevention of ischemic stroke,
its effect on stroke severity and early outcome is still controversial. We aimed to evaluate the …

Influence of statin pretreatment on initial neurological severity and short-term functional outcome in acute ischemic stroke patients: The fukuoka stroke registry

H Ishikawa, Y Wakisaka, R Matsuo… - Cerebrovascular …, 2016 - karger.com
Background: Statins have neuroprotective effects against ischemic stroke. However,
associations between pre-stroke statin treatment and initial stroke severity and between the …

Statin administration prior to ischaemic stroke onset and survival: exploratory evidence from matched treatment–control study

S Aslanyan, CJ Weir, GT McInnes… - European journal of …, 2005 - Wiley Online Library
In addition to their lipid‐lowering effects, it has been speculated that statins may also have
beneficial effects on cerebral circulation and brain parenchyma during ischaemic stroke and …

Statin use and high-dose statin use after ischemic stroke in the UK: a retrospective cohort study

Z Yang, D Edwards, E Massou, CL Saunders… - Clinical …, 2019 - Taylor & Francis
Background: Trial evidence supports statin use after ischemic stroke and recent American,
European and British guidelines recommend high-intensity statins for this indication. Limited …

[HTML][HTML] Statins in acute ischemic stroke: a systematic review

KS Hong, JS Lee - Journal of stroke, 2015 - ncbi.nlm.nih.gov
Background and Purpose Statins have pleiotropic effects of potential neuroprotection.
However, because of lack of large randomized clinical trials, current guidelines do not …

Lack of statin therapy and outcomes after ischemic stroke: a population-based study

J Åivo, JO Ruuskanen, A Tornio, P Rautava, V Kytö - Stroke, 2023 - Am Heart Assoc
Background: Statin treatment is effective at preventing adverse vascular events after
ischemic stroke (IS). However, many patients fail to use statins after IS. We studied the …

Association between acute statin therapy, survival, and improved functional outcome after ischemic stroke: the North Dublin Population Stroke Study

D Ní Chróinín, EL Callaly, J Duggan, Á Merwick… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Statins improve infarct volume and neurological outcome in
animal stroke models. We investigated the relationship between statin therapy and ischemic …