There is mounting evidence from studies on experimental cancer in rodents, interventional
studies in patients with familial adenomatous polyposis, and some, but not all, epidemiologic …

Large bowel cancer is not only the third most frequent cancer in the world but is one of the
most common human malignancies in Western countries, including North America. In recent …

The hypothesis that aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) might
protect against colorectal, and possibly other cancers, arose in the mid-1970s when higher …

▪ Abstract Nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, appear to have
clinically significant anticarcinogenic effects in the gastrointestinal tract. Epidemiological …

Increasing evidence suggests that aspirin and other nonsteroidal anti-inflammatory drugs
(NSAIDs) reduce the risk of colorectal cancer. This observation is supported by results from …

Colorectal cancer is the second leading cause of death from cancer in the United States.
Differences in dietary habits and lifestyles among populations in different geographic …

In recent years, several areas of biological research have increasingly supported the
suggestion that aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) may …

Large bowel cancer is one of the most common human malignancies in western countries,
including North America. Several epidemiological studies have detected decreases in the …

Epidemiologic studies indicate strongly that aspirin use reduces the risk of colorectal cancer
and adenoma by approximately 40 to 50%. Perhaps up to ten years of use may be required …

During recent years, multidisciplinary studies in epidemiology and molecular biology, as
well as preclinical studies, have contributed much to our understanding of the etiology of …