Objective The purpose of this observational study was to examine the association of protein
and genetic biomarkers with pain and pain-related disability in individuals with axial low …

Molecular events that drive disc damage and low back pain (LBP) may precede clinical
manifestation of disease onset and can cause detrimental long-term effects such as …

Background Treatment outcome of low back pain (LBP) is associated with inter-individual
variations in pain relief and functional disability. Genetic variants of catechol-O …

Background context Epidural corticosteroid injections are commonly used to treat back and
leg pain associated with lumbar spinal stenosis. However, little is known about which patient …

Purpose To examine the association between COMT and OPRM1 gene polymorphisms and
pain and disability at baseline and long-term follow-up in patients treated for chronic low …

Sex differences in clinical and experimental pain responses have been widely reported;
however, few studies have examined sex differences in outcomes from interventional pain …

The relationship between disc degeneration, low back pain, and human pain genetics -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Pain affects most individuals with traumatic spinal cord injury (SCI). Major pain types after
SCI are neuropathic or nociceptive, often experienced concurrently. Pain after SCI may be …

Objectives Chronic pain is one of the most common reasons individuals seek medical
attention. It is a major issue because of the wide interindividual variability in the analgesic …

Purpose Lumbar spinal stenosis (LSS) is common in our aging population resulting in pain
and functional impairment. Recent advances in pain research have identified several single …