Post‐transcriptional gene regulation in the biology and virulence of Candida albicans

J Verma‐Gaur, A Traven - Cellular microbiology, 2016 - Wiley Online Library
In the human fungal pathogen Candida albicans, remodelling of gene expression drives
host adaptation and virulence. Recent studies revealed that in addition to transcription, post …

Control of Candida albicans morphology and pathogenicity by post-transcriptional mechanisms

D Kadosh - Cellular and molecular life sciences, 2016 - Springer
Candida albicans is a major human fungal pathogen responsible for both systemic and
mucosal infections in a wide variety of immunocompromised individuals. Because the ability …

Overexpression approaches to advance understanding of Candida albicans

LS Rai, L van Wijlick, M Chauvel… - Molecular …, 2022 - Wiley Online Library
Candida albicans is an opportunistic fungal pathogen that is responsible for infections linked
to high mortality. Loss‐of‐function approaches, taking advantage of gene knockouts or …

From commensal to pathogen: stage-and tissue-specific gene expression of Candida albicans

B Hube - Current opinion in microbiology, 2004 - Elsevier
Candida albicans is both a successful commensal and pathogen of humans that can infect a
broad range of body sites. The transition from commensalism to parasitism requires a …

Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans

D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …

Infection-related gene expression in Candida albicans

AJP Brown, FC Odds, NAR Gow - Current opinion in microbiology, 2007 - Elsevier
Research into the major fungal pathogen, Candida albicans has firmly entered the post-
genomics era. The current challenge is to apply these technologies to the analysis of C …

Transcriptional Circuits Regulating Developmental Processes in Candida albicans

DL Rodriguez, MM Quail, AD Hernday… - Frontiers in Cellular and …, 2020 - frontiersin.org
Candida albicans is a commensal member of the human microbiota that colonizes multiple
niches in the body including the skin, oral cavity, and gastrointestinal and genitourinary …

Infection-Associated Genes of Candida Albicans

B Hube - Future microbiology, 2006 - Taylor & Francis
Advances in the medical treatment of life-threatening disorders have increased the
population of patients that are more susceptible to opportunistic microbial infections, such as …

BRG1 and NRG1 form a novel feedback circuit regulating Candida albicans hypha formation and virulence

IA Cleary, AL Lazzell, C Monteagudo… - Molecular …, 2012 - Wiley Online Library
In the opportunistic fungal pathogen Candida albicans both cellular morphology and the
capacity to cause disease are regulated by the transcriptional repressor Nrg1p. One of the …

Transcriptional Response of Candida albicans upon Internalization by Macrophages

MC Lorenz, JA Bender, GR Fink - Eukaryotic cell, 2004 - Am Soc Microbiol
The opportunistic fungal pathogen Candida albicans is both a benign gut commensal and a
frequently fatal systemic pathogen. The interaction of C. albicans with the host's innate …