[HTML][HTML] Cardiac tissue engineering for the treatment of hypoplastic left heart syndrome (HLHS)

R Abraham, L Vricella, N Hibino - Translational pediatrics, 2023 - ncbi.nlm.nih.gov
Hypoplastic left heart syndrome (HLHS) is a deadly congenital heart disease that arises
when the left ventricle and outflow tract fail to develop appropriately, inhibiting the adequate …

Regenerative medicine strategies for hypoplastic left heart syndrome

J Chery, J Wong, S Huang, S Wang… - Tissue Engineering Part B …, 2016 - liebertpub.com
Hypoplastic left heart syndrome (HLHS), the most severe and common form of single
ventricle congenital heart lesions, is characterized by hypoplasia of the mitral valve, left …

[HTML][HTML] Cell-based therapy to boost right ventricular function and cardiovascular performance in hypoplastic left heart syndrome: Current approaches and future …

K Williams, A Khan, YS Lee, JM Hare - Seminars in perinatology, 2023 - Elsevier
Congenital heart disease remains one of the most frequently diagnosed congenital diseases
of the newborn, with hypoplastic left heart syndrome (HLHS) being considered one of the …

Stem cell therapy for hypoplastic left heart syndrome: mechanism, clinical application, and future directions

GJ Bittle, D Morales, KB Deatrick, N Parchment… - Circulation …, 2018 - Am Heart Assoc
Hypoplastic left heart syndrome is a type of congenital heart disease characterized by
underdevelopment of the left ventricle, outflow tract, and aorta. The condition is fatal if …

Hypoplastic left heart syndrome: From bedside to bench and back

A Saraf, WM Book, TJ Nelson, C Xu - Journal of molecular and cellular …, 2019 - Elsevier
Abstract Hypoplastic Left Heart Syndrome (HLHS) is a complex Congenital Heart Disease
(CHD) that was almost universally fatal until the advent of the Norwood operation in 1981 …

Stem cell therapy for single ventricle congenital heart disease–current state and future directions

A Bilewska, R Mishra, A Stefanowicz… - … Cardiology/Postępy w …, 2022 - termedia.pl
Hypoplastic left heart syndrome (HLHS) is one of the most complex forms of congenital heart
disease, characterized by an underdeveloped left ventricle, outflow tract and aorta. Current …

Regenerative therapy for hypoplastic left heart syndrome: First report of intraoperative intramyocardial injection of autologous umbilical-cord blood–derived cells

HM Burkhart, MY Qureshi, SC Peral, PW O'Leary… - The Journal of thoracic …, 2015 - jtcvs.org
The current standard of care for neonates with hypoplastic left heart syndrome (HLHS)
includes a series of cardiac operations culminating in a complete cavopulmonary …

[HTML][HTML] The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome

JM Kelly, C Anderson, CK Breuer - Journal of Cardiovascular …, 2022 - mdpi.com
The development and translation of regenerative medicine approaches for the treatment of
hypoplastic left heart syndrome (HLHS) provides a promising alternative to the current …

[HTML][HTML] Current state of the art in hypoplastic left heart syndrome

AK Birla, S Brimmer, WD Short, OO Olutoye… - Frontiers in …, 2022 - frontiersin.org
Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease in which a
neonate is born with an underdeveloped left ventricle and associated structures. Without …

[PDF][PDF] Dissecting the left heart hypoplasia by pluripotent stem cells

J Kobayashi, S Sano, H Oh - Etiology and Morphogenesis of …, 2016 - library.oapen.org
The genetic background of hypoplastic left heart syndrome (HLHS) is still unknown. Cardiac
differentiation from pluripotent stem cells (PSCs) can recapitulate the cardiogenesis in vitro …