Characterization of the endokinins: human tachykinins with cardiovascular activity

NM Page, NJ Bell, SM Gardiner… - Proceedings of the …, 2003 - National Acad Sciences
We report four human tachykinins, endokinins A, B, C, and D (EKA–D), encoded from a
single tachykinin precursor 4 gene that generates four mRNAs (α, β, γ, and δ). Tachykinin 4 …

Newly discovered tachykinins raise new questions about their peripheral roles and the tachykinin nomenclature

R Patacchini, A Lecci, P Holzer, CA Maggi - Trends in Pharmacological …, 2004 - cell.com
The tachykinin family has recently been extended by the discovery of a third tachykinin gene
encoding previously unknown mammalian tachykinins (hemokinin 1, endokinin A and …

Characterization of the gene structures, precursor processing and pharmacology of the endokinin peptides

NM Page - Vascular pharmacology, 2006 - Elsevier
The endokinins represent several species-divergent and peripherally located mammalian
tachykinins (hemokinin-1 in mouse and rat, endokinin-1 in rabbit and endokinins A and B in …

Tachykinins and tachykinin receptors: a growing family

JN Pennefather, A Lecci, ML Candenas, E Patak… - Life sciences, 2004 - Elsevier
The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

New challenges in the study of the mammalian tachykinins

NM Page - Peptides, 2005 - Elsevier
There is an expanding repertoire of mammalian tachykinins produced by a variety of
tachykinin genes, gene splicing events and peptide processing. Novel tachykinin-binding …

Pharmacological profile of hemokinin 1: a novel member of the tachykinin family

V Camarda, A Rizzi, G Calo, R Guerrini, S Salvadori… - Life sciences, 2002 - Elsevier
Recently, the cloning of a novel preprotachykinin gene (PPT-C) has been reported. This
gene codes for a novel peptide named hemokinin 1 (HK-1). In contrast with the known …

The mammalian tachykinin receptors

CA Maggi - General pharmacology: The vascular system, 1995 - Elsevier
The mammalian tachykinin receptors - ScienceDirect Skip to main contentSkip to article Elsevier
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Tachykinins: receptor to effector

AM Khawaja, DF Rogers - The international journal of biochemistry & cell …, 1996 - Elsevier
Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …

Tachykinins in the respiratory tract

DA Groneberg, S Harrison, Q Thai Dinh… - Current Drug …, 2006 - ingentaconnect.com
Tachykinins as substance P and neurokinin A belong to a family of peptides, which are
released from airway nerves after noxious stimulation. They influence numerous respiratory …

Tachykinins and the cardiovascular system

DA Walsh, DF McWilliams - Current drug targets, 2006 - ingentaconnect.com
The tachykinin family of vasoactive peptides comprises the neuropeptides substance P,
neurokinin A and neurokinin B, and the newly discovered endokinins and hemokinins. Their …