The genetic program of genital human papillomaviruses in infection and cancer

LP Turek, EM Smith - Obstetrics and Gynecology Clinics, 1996 - obgyn.theclinics.com
Unlike most other solid tumors in humans, carcinoma of the uterine cervix is associated with
concomitant infection by a small DNA tumor virus, one (or, rarely, more than one) of several …

Differentiation-dependent chromatin rearrangement coincides with activation of human papillomavirus type 31 late gene expression

LM Peña, LA Laimins - Journal of virology, 2001 - Am Soc Microbiol
The life cycle of human papillomaviruses (HPVs) is tightly linked to the differentiation status
of the host cell. While early genes are expressed during the initial stages of viral infection …

Molecular biology of human papillomavirus infection and cervical cancer

J Doorbar - Clinical science, 2006 - portlandpress.com
HPVs (human papillomaviruses) infect epithelial cells and cause a variety of lesions ranging
from common warts/verrucas to cervical neoplasia and cancer. Over 100 different HPV types …

The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review

SV Graham - Clinical science, 2017 - portlandpress.com
HPVs (human papillomaviruses) infect epithelial cells and their replication cycle is intimately
linked to epithelial differentiation. There are over 200 different HPV genotypes identified to …

Human papillomaviruses; epithelial tropisms, and the development of neoplasia

N Egawa, K Egawa, H Griffin, J Doorbar - Viruses, 2015 - mdpi.com
Papillomaviruses have evolved over many millions of years to propagate themselves at
specific epithelial niches in a range of different host species. This has led to the great …

New concepts on the role of human papillomavirus in cell cycle regulation

SM Syrjänen, KJ Syrjänen - Annals of medicine, 1999 - Taylor & Francis
Human papillomaviruses (HPVs) are strictly host-specific and also show a distinct tropism to
squamous epithelial cells. Upon HPV infection, only a portion of the virus reaching the …

[HTML][HTML] Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma

F Thierry - Virology, 2009 - Elsevier
Human papillomaviruses (HPV) are small DNA viruses that contain a compact and non-
redundant genome. HPV, with the help of only few genes, can achieve a complete …

Principles of epithelial homeostasis control during persistent human papillomavirus infection and its deregulation at the cervical transformation zone

J Doorbar, K Zheng, A Aiyenuro, W Yin… - Current Opinion in …, 2021 - Elsevier
Human papillomaviruses establish a reservoir of infection in the epithelial basal layer. To do
this they limit their gene expression to avoid immune detection and modulate epithelial …

Hitchhiking on host chromatin: how papillomaviruses persist

AA McBride, N Sakakibara, WH Stepp… - Biochimica et Biophysica …, 2012 - Elsevier
Persistent viruses need mechanisms to protect their genomes from cellular defenses and to
ensure that they are efficiently propagated to daughter host cells. One mechanism by which …

Human papillomavirus molecular biology and disease association

J Doorbar, N Egawa, H Griffin… - Reviews in medical …, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …