From Polymer to Size‐Defined Oligomers: A Highly Divergent and Stereocontrolled Construction of Chondroitin Sulfate A, C, D, E, K, L, and M Oligomers from a Single …

JC Jacquinet, C Lopin‐Bon… - Chemistry–A European …, 2009 - Wiley Online Library
An efficient, stereocontrolled, and highly divergent approach for the preparation of oligomers
of chondroitin sulfate (CS) A, C, D, E, K, L, and M variants, starting from a single precursor …

[引用][C] From polymer to size‐defined oligomers: An expeditious route for the preparation of chondroitin oligosaccharides

C Lopin, JC Jacquinet - Angewandte Chemie, 2006 - Wiley Online Library
Since the pioneering works of Levene [6] and of Davidson and Meyer [7] on the structure of
chondroitin sulfates, chondrosine, the basic repeating unit of chondroitin sulfates, can be …

Recent advances in the chemical and enzymatic chondroitin sulfate synthesis

A Vibert, JC Jacquinet, C Lopin-Bon - Journal of Carbohydrate …, 2011 - Taylor & Francis
Chondroitin sulfates (CSs) are complex polysaccharides that play important roles in many
biological processes. This mini-review focuses on the recent advances in chemical and …

Synthesis of structurally defined chondroitin sulfate: Paving the way to the structure-activity relationship studies

Y Ji, S Zhang, M Qiao, R Jiao, J Li, P Song… - Carbohydrate …, 2020 - Elsevier
Chondroitin sulfate (CS) is one of the major and widespread glycosaminoglycans, a family of
structurally complex, linear, anionic hetero-co-polysaccharides. CS plays a vital role in …

Enzymatic synthesis of homogeneous chondroitin sulfate oligosaccharides

J Li, G Su, J Liu - Angewandte Chemie International Edition, 2017 - Wiley Online Library
Chondroitin sulfate (CS) is a sulfated polysaccharide that plays essential physiological roles.
Here, we report an enzyme‐based method for the synthesis of a library of 15 different CS …

Semi‐Synthesis of Unusual Chondroitin Sulfate Polysaccharides Containing GlcA(3‐O‐sulfate) or GlcA(2,3‐di‐O‐sulfate) Units

E Bedini, C De Castro, M De Rosa… - … A European Journal, 2012 - Wiley Online Library
The extraction from natural sources of Chondroitin sulfate (CS), a polysaccharide used for
management of osteoarthritis, leads to very complex mixtures. The synthesis of CS by …

From Polymer to Size‐Defined Oligomers: A Step Economy Process for the Efficient and Stereocontrolled Construction of Chondroitin Oligosaccharides and …

A Vibert, C Lopin‐Bon… - Chemistry–A European …, 2009 - Wiley Online Library
Controlled acid hydrolysis of polymeric chondroitin sulfate of bovine origin afforded in good
yield a basic disaccharide fragment that was used for the first time as a starting material for …

Synthetic and semi-synthetic chondroitin sulfate oligosaccharides, polysaccharides, and glycomimetics

E Bedini, M Parrilli - Carbohydrate research, 2012 - Elsevier
Chondroitin sulfate (CS) is a sulfated polysaccharide involved in a myriad of biological
processes. Due to the variable sulfation pattern of CS polymer chains, the need to study in …

Semisynthesis of chondroitin sulfate oligosaccharides based on the enzymatic degradation of chondroitin

X Zhang, H Liu, W Yao, X Meng, Z Li - The Journal of organic …, 2019 - ACS Publications
Chondroitin sulfate (CS) is a structurally complex polyanionic glycosaminoglycan that plays
essential roles in physiological processes. Here we report a facile approach to a library of …

Development of semisynthetic, regioselective pathways for accessing the missing sulfation patterns of chondroitin sulfate

G Vessella, S Traboni, D Cimini, A Iadonisi… - …, 2019 - ACS Publications
Chondroitin sulfate (CS) is a glycosaminoglycan playing several biological functions, which
seem to be encoded through its sulfation pattern. This “sulfation code” is still to be …