Transthyretin (TTR) is a thyroid hormone-binding protein which transports thyroxine from the
bloodstream to the brain. The structural stability of TTR in tetrameric form is crucial for …

Hereditary amyloidogenic transthyretin (TTR)(ATTR) amyloidosis is an autosomal dominant
form of fatal hereditary amyloidosis. Owing to progress in biochemical and molecular genetic …

Hereditary transthyretin amyloidosis (ATTRv) is a severe, adult-onset autosomal dominant
inherited systemic disease predominantly affecting the peripheral and autonomic nervous …

Transthyretin (TTR) amyloidoses are systemic diseases associated with TTR aggregation
and extracellular deposition in tissues as amyloid. The most frequent and severe forms of …

Transthyretin (TTR) amyloidosis is caused by systemic deposition of wild-type or variant
amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis has …

Transthyretin (TTR) is a homotetrameric serum and cerebrospinal fluid protein that
transports both thyroxine (T4) and the retinol-retinol binding protein complex (holoRBP) …

Amyloidoses represent a group of diseases characterized by the pathological accumulation
in the extracellular area of insoluble misfolded protein material called “amyloid”. The …

Introduction: Hereditary transthyretin-mediated amyloidosis (ATTRv; v for variant) is a rare,
progressive, fatal multi-systemic disease, autosomal dominantly inherited with …

Transthyretin (TTR) amyloidosis (ATTR amyloidosis) is an underdiagnosed and important
type of cardiomyopathy and/or polyneuropathy that requires increased awareness within the …

Amyloidosis is a group of conditions characterized by the accumulation of amyloid deposits
in various tissues. Among these disorders, ATTR amyloidosis occurs either with or without a …