Physiological pattern of disease assessed by pressure-wire pullback has an influence on fractional flow reserve/instantaneous wave-free ratio discordance: Insights …

T Warisawa, CM Cook, JP Howard… - Circulation …, 2019 - Am Heart Assoc
Background: Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) disagree
on the hemodynamic significance of a coronary lesion in≈ 20% of cases. It is unknown …

Impact of physiologically diffuse versus focal pattern of coronary disease on quantitative flow reserve diagnostic accuracy

R Scarsini, S Fezzi, G Pesarini… - Catheterization and …, 2022 - Wiley Online Library
Background Fractional flow reserve (FFR) and instantaneous wave‐free ratio (iFR) disagree
in about 20% of intermediate coronary lesions. As the physiological pattern of coronary …

Hemodynamic and Lesion Characteristics Associated with Discordance between the Instantaneous Wave‐Free Ratio and Fractional Flow Reserve

H Arashi, N Satomi, I Ishida… - Journal of …, 2019 - Wiley Online Library
Background. The instantaneous wave‐free ratio (iFR) is an invasive coronary physiological
index that is not inferior to fractional flow reserve‐(FFR‐) guided revascularization. The …

Baseline instantaneous wave-free ratio as a pressure-only estimation of underlying coronary flow reserve: results of the JUSTIFY-CFR Study (Joined Coronary …

R Petraco, TP Van De Hoef, S Nijjer, S Sen… - Circulation …, 2014 - Am Heart Assoc
Background—Coronary flow reserve has extensive validation as a prognostic marker in
coronary disease. Although pressure-only fractional flow reserve (FFR) improves outcomes …

Diagnostic performance of the instantaneous wave-free ratio: comparison with fractional flow reserve

S De Rosa, A Polimeni, R Petraco… - Circulation …, 2018 - Am Heart Assoc
Background—Aim of the present study was to perform a meta-analysis of all available
studies comparing the instantaneous wave-free ratio (iFR) with fractional flow reserve (FFR) …

Instantaneous wave-free ratio versus fractional flow reserve to guide PCI

M Götberg, EH Christiansen… - … England Journal of …, 2017 - Mass Medical Soc
Background The instantaneous wave-free ratio (iFR) is an index used to assess the severity
of coronary-artery stenosis. The index has been tested against fractional flow reserve (FFR) …

Fractional Flow Reserve Versus Instantaneous Wave‐Free Ratio in Assessment of Lesion Hemodynamic Significance and Explanation of their Discrepancies …

T Kovarnik, M Hitoshi, A Kral, S Jerabek… - Journal of the …, 2022 - Am Heart Assoc
Background The FiGARO (FFR versus iFR in Assessment of Hemodynamic Lesion
Significance, and an Explanation of Their Discrepancies) trial is a prospective registry …

Physiologic characteristics and clinical outcomes of patients with discordance between FFR and iFR

SH Lee, KH Choi, JM Lee, D Hwang, TM Rhee… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study evaluated the physiologic characteristics of discordant lesions
between instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) and the …

Revisiting the optimal fractional flow reserve and instantaneous wave-free ratio thresholds for predicting the physiological significance of coronary artery disease

BN Modi, H Rahman, T Kaier, M Ryan… - Circulation …, 2018 - Am Heart Assoc
Background: There has been a gradual upward creep of revascularization thresholds for
both fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR), before the clinical …

Diagnostic performance of angiogram-derived fractional flow reserve: a pooled analysis of 5 prospective cohort studies

G Witberg, B De Bruyne, WF Fearon… - Cardiovascular …, 2020 - jacc.org
Objectives This study sought to assess the diagnostic performance of FFRangio (CathWorks,
Kfar Saba, Israel), an angiogram-derived fractional flow reserve (FFR) technology …