Does the extent of neck surgery based on preoperative calcitonin level influence survival in medullary thyroid carcinoma: a retrospective tertiary centre experience

W Ansley, A Kamyab, L Noden… - The Annals of The …, 2024 - publishing.rcseng.ac.uk
Introduction Medullary thyroid carcinoma (MTC) is a rare thyroid cancer arising from the
calcitonin-secreting parafollicular cells. Previous studies suggested a preoperative …

[HTML][HTML] The role of calcitonin in predicting the extent of surgery in medullary thyroid carcinoma: a nationwide population-based study in Norway

EM Opsahl, LA Akslen, E Schlichting… - European thyroid …, 2019 - etj.bioscientifica.com
Background: Preoperative predictors for the need of prophylactic lymph node dissection in
the lateral neck have been studied in patients with medullary thyroid carcinoma (MTC) …

Prophylactic lateral neck dissection for medullary thyroid carcinoma is not associated with improved survival

PM Spanheimer, I Ganly, JF Chou, M Capanu… - Annals of surgical …, 2021 - Springer
Background Patients with medullary thyroid carcinoma (MTC) often receive lateral lymph
node dissection with total thyroidectomy when calcitonin levels are elevated, even in the …

Lymph node metastases and elevated postoperative calcitonin: predictors of poor survival in medullary thyroid carcinoma

P Siironen, J Hagström, HO Mäenpää, J Louhimo… - Acta …, 2016 - Taylor & Francis
Background Total thyroidectomy is the treatment of choice for medullary thyroid carcinoma
(MTC), but the extent of neck dissection is controversial. Lymph node metastases, distant …

Can Calcitonin Levels Guide Prophylactic Neck Dissection in Sporadic Medullary Thyroid Carcinoma?

EJ Han, KK Bommakanti, MA St. John - The Laryngoscope, 2024 - Wiley Online Library
BACKGROUND Medullary thyroid carcinoma (MTC) comprises less than 5% of thyroid
cancers but is responsible for over 10% of deaths related to thyroid cancer. MTC arises from …

[HTML][HTML] Preoperative identification of low-risk medullary thyroid carcinoma: potential application to reduce total thyroidectomy

H Park, HJ Ryu, J Heo, MK Chung, YI Son, JH Kim… - Scientific Reports, 2023 - nature.com
Current guidelines recommend total thyroidectomy with central lymph node dissection
(CND) for patients with medullary thyroid carcinoma (MTC). This study aimed to identify low …

Calcitonin secretory index and unsuspected nodal disease in medullary thyroid carcinoma

S Filimon, RJ Payne, MJ Black, MP Hier, AM Mlynarek… - Endocrine Practice, 2018 - Elsevier
Objective: Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy originating from
parafollicular C-cells with the potential for aggressive behavior. The extent of lymph node …

Is intraoperative calcitonin monitoring useful to modulate the extension of neck dissection in patients with medullary thyroid carcinoma?

C De Crea, M Raffaelli, V Milano… - World journal of …, 2014 - Wiley Online Library
Background The extension of the compartment‐oriented neck dissection at primary surgery
in medullary thyroid carcinoma (MTC) is controversial. Because a< 50% decrease in …

Hemithyroidectomy for medullary thyroid carcinoma: possible de-escalation strategy based on preoperative calcitonin levels

H Coerts, D Aykan, L Lodewijk, WE Visser… - European Journal of …, 2024 - ejso.com
Background: The current recommended surgical strategy for medullary thyroid carcinoma is
a total thyroidectomy, removal of all neoplastic tissue present in the neck and bilateral …

[HTML][HTML] Timing and extension of lymphadenectomy in medullary thyroid carcinoma: a case series from a single institution

A Polistena, A Sanguinetti, R Lucchini… - International Journal of …, 2017 - Elsevier
Background Medullary thyroid carcinoma is an aggressive tumor and presents with
significant morbidity and mortality and a high rate of lymph node metastases. The …