Eicosapentaenoic and docosahexaenoic acid-enriched high fat diet delays the development of fatty liver in mice
Background Low hepatic content of n-3 PUFA has been associated with NAFLD in humans.
Whether this is associated with reduced dietary intake or increased turnover of these FA is …
Whether this is associated with reduced dietary intake or increased turnover of these FA is …
Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets
BD Pachikian, A Essaghir, JB Demoulin, AM Neyrinck… - PloS one, 2011 - journals.plos.org
Patients with non-alcoholic fatty liver disease are characterised by a decreased n-3/n-6
polyunsaturated fatty acid (PUFA) ratio in hepatic phospholipids. The metabolic …
polyunsaturated fatty acid (PUFA) ratio in hepatic phospholipids. The metabolic …
Protective effects of various ratios of DHA/EPA supplementation on high-fat diet-induced liver damage in mice
T Shang, L Liu, J Zhou, M Zhang, Q Hu, M Fang… - Lipids in Health and …, 2017 - Springer
Background A sedentary lifestyle and poor diet are risk factors for the progression of non-
alcoholic fatty liver disease. However, the pathogenesis of hepatic lipid accumulation is not …
alcoholic fatty liver disease. However, the pathogenesis of hepatic lipid accumulation is not …
Dietary DHA/EPA Ratio Changes Fatty Acid Composition and Attenuates Diet‐Induced Accumulation of Lipid in the Liver of ApoE−/− Mice
L Liu, Q Hu, H Wu, X Wang, C Gao… - Oxidative Medicine …, 2018 - Wiley Online Library
Diets containing various docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) ratios
protect against liver damage in mice fed with a high‐fat diet (HFD). However, it is unclear …
protect against liver damage in mice fed with a high‐fat diet (HFD). However, it is unclear …
Fish oil decreases hepatic lipogenic genes in rats fasted and refed on a high fructose diet
Fasting and then refeeding on a high-carbohydrate diet increases serum and hepatic
triacylglycerol (TAG) concentrations compared to standard diets. Fructose is a lipogenic …
triacylglycerol (TAG) concentrations compared to standard diets. Fructose is a lipogenic …
Effects of long-term DHA supplementation and physical exercise on non-alcoholic fatty liver development in obese aged female mice
J Yang, N Sáinz, E Félix-Soriano, E Gil-Iturbe… - Nutrients, 2021 - mdpi.com
Obesity and aging are associated to non-alcoholic fatty liver disease (NAFLD) development.
Here, we investigate whether long-term feeding with a docosahexaenoic acid (DHA) …
Here, we investigate whether long-term feeding with a docosahexaenoic acid (DHA) …
Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition
MJJ Ronis, JN Baumgardner… - Physiological …, 2012 - journals.physiology.org
To determine if dietary fat composition affects the progression of nonalcoholic fatty liver
disease (NAFLD), we overfed male Sprague-Dawley rats low (5%) or high (70%) fat diets …
disease (NAFLD), we overfed male Sprague-Dawley rats low (5%) or high (70%) fat diets …
Dietary Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) Operate by Different Mechanisms to Modulate Hepatic Steatosis and Hyperinsulemia in fa/fa …
L Hong, P Zahradka, L Cordero-Monroy, B Wright… - Nutrients, 2019 - mdpi.com
Hepatic steatosis, an early stage of non-alcoholic fatty liver disease, is commonly present in
obesity and type 2 diabetes, and is associated with reduced hepatic omega-3 …
obesity and type 2 diabetes, and is associated with reduced hepatic omega-3 …
Hepatic steatosis in n-3 fatty acid depleted mice: focus on metabolic alterations related to tissue fatty acid composition
BD Pachikian, AM Neyrinck, PD Cani, L Portois… - BMC physiology, 2008 - Springer
Background There are only few data relating the metabolic consequences of feeding diets
very low in n-3 fatty acids. This experiment carried out in mice aims at studying the impact of …
very low in n-3 fatty acids. This experiment carried out in mice aims at studying the impact of …
Ability of high fat diet to induce liver pathology correlates with the level of linoleic acid and Vitamin E in the diet
Increased uptake of fat, such as through the ingestion of high fat diet (HFD), can lead to fatty
liver diseases and metabolic syndrome. It is not clear whether certain fatty acids may be …
liver diseases and metabolic syndrome. It is not clear whether certain fatty acids may be …