Development and validation of a novel lipid metabolism-related gene prognostic signature and candidate drugs for patients with bladder cancer

K Zhu, L Xiaoqiang, W Deng, G Wang, B Fu - Lipids in health and disease, 2021 - Springer
Background Bladder cancer (BLCA) is a common cancer associated with an unfavorable
prognosis. Increasing numbers of studies have demonstrated that lipid metabolism affects …

A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer

C Zhang, X Gou, W He, H Yang, H Yin - Cancer cell international, 2020 - Springer
Background Bladder cancer is one of the most prevalent malignancies worldwide. However,
traditional indicators have limited predictive effects on the clinical outcomes of bladder …

A novel metabolic subtype with S100A7 high expression represents poor prognosis and immuno-suppressive tumor microenvironment in bladder cancer

Y Cai, Y Cheng, Z Wang, L Li, Z Qian, W Xia, W Yu - BMC cancer, 2023 - Springer
Background Bladder cancer (BLCA) represents a highly heterogeneous disease
characterized by distinct histological, molecular, and clinical features, whose tumorigenesis …

Identification of a prognostic gene signature based on an immunogenomic landscape analysis of bladder cancer

Y Luo, L Chen, Q Zhou, Y Xiong… - Journal of cellular …, 2020 - Wiley Online Library
Cancer immune plays a critical role in cancer progression. Tumour immunology and
immunotherapy are one of the exciting areas in bladder cancer research. In this study, we …

Identification and validation of an individualized prognostic signature of bladder cancer based on seven immune related genes

H Qiu, X Hu, C He, B Yu, Y Li, J Li - Frontiers in genetics, 2020 - frontiersin.org
Background There has been no report of prognostic signature based on immune-related
genes (IRGs). This study aimed to develop an IRG-based prognostic signature that could …

Immunogenomic characteristics of cell-death-associated genes with prognostic implications in bladder cancer

W Xu, HJ Tang, A Anwaier, W Liu, X Tian, J Su… - Frontiers in …, 2022 - frontiersin.org
Bladder cancer is one of the most common genitourinary malignant cancers worldwide. Cell
death processes, including apoptosis, ferroptosis, and necrosis, provide novel clinical and …

Development and validation of a molecular prognostic index of bladder cancer based on immunogenomic landscape analysis

N Xu, ZB Ke, XD Lin, YH Chen, YP Wu, Y Chen… - Cancer cell …, 2020 - Springer
Abstract Background Bladder cancer (BCa) is one of the important tumors that have been
proven to be treatable with immunotherapy. This study aims to identify and validate a …

In silico development and clinical validation of novel 8 gene signature based on lipid metabolism related genes in colon adenocarcinoma

C Jiang, Y Liu, S Wen, C Xu, L Gu - Pharmacological research, 2021 - Elsevier
Background Changes in lipid metabolism pathways play a major role in colon
carcinogenesis and development. Hence, we conducted a systematic analysis of lipid …

Multi-omics reveals novel prognostic implication of SRC protein expression in bladder cancer and its correlation with immunotherapy response

W Xu, A Anwaier, C Ma, W Liu, X Tian… - Annals of …, 2021 - Taylor & Francis
Purpose This study aims to identify potential prognostic biomarkers of bladder cancer (BCa)
based on large-scale multi-omics data and investigate the role of SRC in improving …

Identification of a tumor microenvironment-related seven-gene signature for predicting prognosis in bladder cancer

Z Wang, L Tu, M Chen, S Tong - BMC cancer, 2021 - Springer
Background Accumulating evidences demonstrated tumor microenvironment (TME) of
bladder cancer (BLCA) may play a pivotal role in modulating tumorigenesis, progression …