Background Esophageal adenocarcinoma (EAC) is a molecularly heterogeneous disease
with poor prognosis that is rising rapidly in incidence. We aimed to demonstrate specific …

Esophageal cancers, largely adenocarcinoma in Western countries and squamous cell
cancer in Asia, present a significant burden of disease and remain one of the most lethal of …

Background. Early detection and complete resection are important prognostic factors for
esophageal cancer (EC). Intraoperative molecular imaging (IMI) using tumor-targeted …

Advanced esophageal cancer, whether squamous cell or adenocarcinoma associated with
Barrett's disease, carries a dismal prognosis. Dysplasia and early carcinoma, however, are …

Molecular imaging in endoscopy uses the molecular signature of cells for targeted imaging
of GI pathologies. Advances of molecular imaging have been driven by the clinical need for …

Malignant tumors of the esophagus continue to be a major health issue associated with high
mortality primarily because most present with symptoms of dysphagia or anaemia. The …

Multimodal endoscopy using fluorescence molecular probes is a promising method of
surveying the entire esophagus to detect cancer progression. Using the fluorescence ratio of …

Background and study aims We investigated the effect of adding magnifying blue laser
imaging (BLI), magnifying narrow-band imaging (NBI), and iodine staining to white light …

Clinical workflows for the non-invasive detection and characterization of disease states
could benefit from optical-imaging biomarkers. In this Perspective, we discuss opportunities …

Gastrointestinal (GI) neoplasia is a leading contributor to global cancer mortality and
morbidity. 1 Early detection of cancers of the GI tract significantly improves patient a …