Both genetic susceptibility and environmental factors are important contributors to
autoimmune disease pathogenesis. As an environmental factor, the gut microbiome plays a …

Immune checkpoint inhibitors (ICIs) therapy is a novel strategy for cancer treatments in
recent years. However, it was observed that most patients treated with ICIs could not get …

Cancer immunotherapists have been searching for biomarkers predicting patient responses
to PD-1/PD-L1 blockade in neoplastic cells as well as in the immune system. Now …

Research has been driven towards finding therapy predictive biomarkers for colorectal
cancer (CRC) with a special interest in studying the gut microbiome. Gut microbiome acts …

Emerging evidence supports that the efficacy of immune checkpoint blockade (ICB) therapy
is associated with the host's gut microbiota, as prior antibiotic intake often leads to poor …

Fecal microbiota transplantation (FMT) has changed the treatment landscape of Clostridium
difficile infection (CDI). Emerging evidence has shown that FMT can also be an effective and …

Fecal microbiota transplantation (FMT) has successfully been applied for the treatment of
recurrent Clostridioides difficile infection (CDI), which has led to studies on its application to …

Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease that results from a
dysregulated immune response against specific environmental triggers in a genetically …

Background The microbiota in the lumen of patients with Crohn's disease (CD) is
characterized by reduced diversity, particularly Firmicutes and Bacteroidetes. It is unknown …

Background & Aims Fecal microbiota transplantation (FMT) can induce remission in patients
with ulcerative colitis (UC). In a randomized controlled trial of FMT in patients with active UC …