While N‐glycan synthesis in the endoplasmic reticulum (ER) is relatively well conserved in
eukaryotes, N‐glycan processing and O‐glycan biosynthesis in the Golgi apparatus are …

Figure 1 N-glycan structures and assembly pathways in wild-type and glycoengineered
plants.(a) Overview of different strategies to modify plant-specific glycan structures. Wild-type …

While plant-based transient expression systems have demonstrated their potency to rapidly
express economically feasible quantities of complex human proteins, less is known about …

Plants are increasingly being used for the production of recombinant proteins. One reason is
that plants are highly amenable to glycan engineering processes and allow the production …

Plant complex-type N-glycans are characterized by the presence of α1, 3-linked fucose
towards the proximal N-acetylglucosamine residue and β1, 2-linked xylose towards the β …

The increasing biotechnological interest in human IgE antibodies demands advanced
systems which allow their proper expression. However, this is still a challenge due to the …

Human immunoglobulin E (IgE) is the most extensively glycosylated antibody isotype so
glycans attached to the seven N-glycosites (NGS) in its Fab and Fc domains may modulate …

A plant transient expression system, with eukaryotic post-translational modification
machinery, offers superior efficiency, scalability, safety, and lower cost over other expression …

Sialic acid, a terminal residue on complex N‐glycans, and branching or antennarity can play
key roles in both the biological activity and circulatory lifetime of recombinant glycoproteins …

GalNAc-type O-glycans are often added to proteins post-translationally in a clustered
manner in repeat regions of proteins, such as mucins and IgA1. Observed IgA1 glycosylation …