Unlocking ancient protein palimpsests
Over the past 30 years, ancient DNA studies have grown from a scientific curiosity into a
powerful research tool with applications in molecular evolution, archaeology, paleontology …
powerful research tool with applications in molecular evolution, archaeology, paleontology …
Ancient protein analysis in archaeology
J Hendy - Science Advances, 2021 - science.org
The analysis of ancient proteins from paleontological, archeological, and historic materials is
revealing insights into past subsistence practices, patterns of health and disease, evolution …
revealing insights into past subsistence practices, patterns of health and disease, evolution …
A guide to ancient protein studies
Palaeoproteomics is an emerging neologism used to describe the application of mass
spectrometry-based approaches to the study of ancient proteomes. As with palaeogenomics …
spectrometry-based approaches to the study of ancient proteomes. As with palaeogenomics …
A comparison of common mass spectrometry approaches for paleoproteomics
TP Cleland, ER Schroeter - Journal of Proteome Research, 2018 - ACS Publications
The last two decades have seen a broad diversity of methods used to identify and/or
characterize proteins in the archeological and paleontological record. Of these, mass …
characterize proteins in the archeological and paleontological record. Of these, mass …
Protein molecular data from ancient (> 1 million years old) fossil material: pitfalls, possibilities and grand challenges
MH Schweitzer, ER Schroeter, MB Goshe - Analytical chemistry, 2014 - ACS Publications
Advances in resolution and sensitivity of analytical techniques have provided novel
applications, including the analyses of fossil material. However, the recovery of original …
applications, including the analyses of fossil material. However, the recovery of original …
Paleoproteomics: an introduction to the analysis of ancient proteins by soft ionisation mass spectrometry
M Buckley - Paleogenomics: Genome-Scale Analysis of Ancient …, 2019 - Springer
The field of proteomic research, analogous to genomic research, has only recently
witnessed a rapid increase in its application to the study of ancient materials. Bone has been …
witnessed a rapid increase in its application to the study of ancient materials. Bone has been …
Ancient DNA analysis
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …
first ancient nuclear genomes could only be characterized after high-throughput sequencing …
Molecular technology in paleontology and paleobiology: Applications and limitations
In the last 5 decades, paleontological research has exploded where fossils have enabled
robust dating of rocks, improved understanding of origination/extinction rates or mass …
robust dating of rocks, improved understanding of origination/extinction rates or mass …
Protein Sequences from Mastodon and Tyrannosaurus Rex Revealed by Mass Spectrometry
JM Asara, MH Schweitzer, LM Freimark, M Phillips… - Science, 2007 - science.org
Fossilized bones from extinct taxa harbor the potential for obtaining protein or DNA
sequences that could reveal evolutionary links to extant species. We used mass …
sequences that could reveal evolutionary links to extant species. We used mass …
Proteomic analysis of a pleistocene mammoth femur reveals more than one hundred ancient bone proteins
We used high-sensitivity, high-resolution tandem mass spectrometry to shotgun sequence
ancient protein remains extracted from a 43 000 year old woolly mammoth (Mammuthus …
ancient protein remains extracted from a 43 000 year old woolly mammoth (Mammuthus …