Tobacco smoke, recognized as a major etiological factor for cancers of the upper
aerodigestive tract, represents an abundant source of reactive oxygen species (ROS), which …

Cigarette smokers inhale a broad range of carcinogens derived from tobacco and its
pyrolysis products, including free radicals, which induce oxidative stress and subsequent …

Cigarette smoking and alcohol consumption, known to cause free radical generation and
lipid peroxidation, are established risk factors for larynx cancer. Malondialdehyde (MDA) is a …

Larynx cancer is strongly associated with tobacco smoking. The objective of this work was
an analysis of aromatic DNA adducts in tumour and non-tumour larynx cells by means of the …

The purpose of this study was to examine the level of smoking‐related aromatic DNA
adducts and oxidative DNA damage in current smokers from a lung cancer case‐control …

Tobacco smoke constituents, 4-aminobiphenyl (4-ABP) and polycyclic aromatic
hydrocarbons (PAH) possess carcinogenic properties as their reactive metabolites form …

Several studies have reported the presence of DNA adducts derived from benzo (a) pyrene
and other polyaromatics by 32P-postlabeling/TLC by measuring diagonal radioactive zones …

The formation of carcinogen-DNA adducts within the respiratory epithelium is thought to be a
critical factor in the induction of lung cancer from tobacco smoke. A reliable surrogate …

Tobacco smoking is a major risk factor for oral cancer; mouth floor and buccal mucosa are
among the most and least cancer‐prone subsites, respectively, in the oral cavity. We …

Epidemiological studies have confirmed the correlation between tobacco smoking,
environmental pollution and the incidence of cancers of the respiratory tract. The occurrence …