[HTML][HTML] Omics-based molecular classifications empowering in precision oncology
Z Zhou, T Lin, S Chen, G Zhang, Y Xu, H Zou, A Zhou… - Cellular Oncology, 2024 - Springer
Background In the past decades, cancer enigmatical heterogeneity at distinct expression
levels could interpret disparities in therapeutic response and prognosis. It built hindrances to …
levels could interpret disparities in therapeutic response and prognosis. It built hindrances to …
Predicting cancer phenotypes with mechanism-driven multi-omics data integration
L Marchionni, D Geman - Cancer Research, 2015 - AACR
Over the past decade technological advances have enabled molecular profiling of human
cancers across distinct genomic domains and other “omes”. The availability of such multi …
cancers across distinct genomic domains and other “omes”. The availability of such multi …
Omics profiling in precision oncology
Cancer causes significant morbidity and mortality worldwide, and is the area most targeted
in precision medicine. Recent development of high-throughput methods enables detailed …
in precision medicine. Recent development of high-throughput methods enables detailed …
Multi-omics analysis: Paving the path toward achieving precision medicine in cancer treatment and immuno-oncology
V Raufaste-Cazavieille, R Santiago… - Frontiers in Molecular …, 2022 - frontiersin.org
The acceleration of large-scale sequencing and the progress in high-throughput
computational analyses, defined as omics, was a hallmark for the comprehension of the …
computational analyses, defined as omics, was a hallmark for the comprehension of the …
Omics in Precision Medicine
Cancer is a multifaceted and complex disease that results from the disruption of genetic,
epigenetic, and metabolic systems responsible for maintaining physiological conditions in …
epigenetic, and metabolic systems responsible for maintaining physiological conditions in …
Precision oncology beyond targeted therapy: combining omics data with machine learning matches the majority of cancer cells to effective therapeutics
Precision oncology involves identifying drugs that will effectively treat a tumor and then
prescribing an optimal clinical treatment regimen. However, most first-line chemotherapy …
prescribing an optimal clinical treatment regimen. However, most first-line chemotherapy …
Artificial intelligence to decode cancer mechanism: beyond patient stratification for precision oncology
The multitude of multi-omics data generated cost-effectively using advanced high-
throughput technologies has imposed challenging domain for research in Artificial …
throughput technologies has imposed challenging domain for research in Artificial …
The need for multi-omics biomarker signatures in precision medicine
Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …
the molecular changes that underlie the development and progression of a wide array of …
Multi-OMICS approaches in cancer biology: New era in cancer therapy
S Chakraborty, G Sharma, S Karmakar… - Biochimica et Biophysica …, 2024 - Elsevier
Innovative multi-omics frameworks integrate diverse datasets from the same patients to
enhance our understanding of the molecular and clinical aspects of cancers. Advanced …
enhance our understanding of the molecular and clinical aspects of cancers. Advanced …
[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes
YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …
generated from the same patients to better understand the molecular and clinical features of …
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