[HTML][HTML] Omics-based molecular classifications empowering in precision oncology

Z Zhou, T Lin, S Chen, G Zhang, Y Xu, H Zou, A Zhou… - Cellular Oncology, 2024 - Springer
Background In the past decades, cancer enigmatical heterogeneity at distinct expression
levels could interpret disparities in therapeutic response and prognosis. It built hindrances to …

Predicting cancer phenotypes with mechanism-driven multi-omics data integration

L Marchionni, D Geman - Cancer Research, 2015 - AACR
Over the past decade technological advances have enabled molecular profiling of human
cancers across distinct genomic domains and other “omes”. The availability of such multi …

Omics profiling in precision oncology

KH Yu, M Snyder - Molecular & Cellular Proteomics, 2016 - ASBMB
Cancer causes significant morbidity and mortality worldwide, and is the area most targeted
in precision medicine. Recent development of high-throughput methods enables detailed …

Multi-omics analysis: Paving the path toward achieving precision medicine in cancer treatment and immuno-oncology

V Raufaste-Cazavieille, R Santiago… - Frontiers in Molecular …, 2022 - frontiersin.org
The acceleration of large-scale sequencing and the progress in high-throughput
computational analyses, defined as omics, was a hallmark for the comprehension of the …

Omics in Precision Medicine

O Kayalar, H Rajabi, D Mortazavi, H Bayram - … , Precision Medicine and …, 2023 - Springer
Cancer is a multifaceted and complex disease that results from the disruption of genetic,
epigenetic, and metabolic systems responsible for maintaining physiological conditions in …

Precision oncology beyond targeted therapy: combining omics data with machine learning matches the majority of cancer cells to effective therapeutics

MQ Ding, L Chen, GF Cooper, JD Young, X Lu - Molecular cancer research, 2018 - AACR
Precision oncology involves identifying drugs that will effectively treat a tumor and then
prescribing an optimal clinical treatment regimen. However, most first-line chemotherapy …

Artificial intelligence to decode cancer mechanism: beyond patient stratification for precision oncology

SK Patel, B George, V Rai - Frontiers in Pharmacology, 2020 - frontiersin.org
The multitude of multi-omics data generated cost-effectively using advanced high-
throughput technologies has imposed challenging domain for research in Artificial …

The need for multi-omics biomarker signatures in precision medicine

M Olivier, R Asmis, GA Hawkins, TD Howard… - International journal of …, 2019 - mdpi.com
Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …

Multi-OMICS approaches in cancer biology: New era in cancer therapy

S Chakraborty, G Sharma, S Karmakar… - Biochimica et Biophysica …, 2024 - Elsevier
Innovative multi-omics frameworks integrate diverse datasets from the same patients to
enhance our understanding of the molecular and clinical aspects of cancers. Advanced …

[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes

YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …