Quality by Design-Guided Systematic Development and Optimization of Mucoadhesive Buccal Films

AAA Hassan, K Kristó, YHEY Ibrahim, G Regdon Jr… - Pharmaceutics, 2023 - mdpi.com
Mucoadhesive buccal films have found increased popularity in pharmaceutical drug delivery
due to the several advantages that they possess. The present study strives to develop and …

Development of a buccal mucoadhesive film for fast dissolution: mathematical rationale, production and physicochemical characterization

MMDC Vila, ER Tardelli, MV Chaud, M Tubino… - Drug Delivery, 2014 - Taylor & Francis
The validity of a mathematical rationale for preparation of a fast-dissolving buccal
mucoadhesive was tested. A buccal mucoadhesive biopolymeric formulation has been …

Determination of dependencies among in vitro and in vivo properties of prepared mucoadhesive buccal films using multivariate data analysis

D Vetchý, H Landová, J Gajdziok, P Doležel… - European Journal of …, 2014 - Elsevier
Mucoadhesive films represent the most developed medical form of buccal application.
Despite the intense focus on buccal film-based systems, there are no standardized methods …

Buccoadhesive drug delivery system: a review

N Sharma, S Jain, S Sardana - Journal of Advanced Pharmacy Education …, 2013 - japer.in
Buccal drug delivery leads direct access to the systemic circulation through the internal
jugular vein bypasses drugs from the hepatic first pass metabolism leading to high …

An overview on natural polymer based mucoadhesive buccal films for controlled drug delivery

A KHADE, G GADGE, U MAHAJAN - International Journal of Pharmacy …, 2020 - ijprt.org
Mucoadhesion is the process where polymers attach to biological substrate or a synthetic or
natural macromolecule, to mucus or an epithelial surface. When the biological substrate is …

Quality by design approach for optimizing preparation and characterization of buccal film formulation with different polymers.

B Aksu, N Coşkunmeriç, G Yeğen… - International …, 2019 - search.ebscohost.com
Bilayered oromucosal film preparations (buccal films) offer a promising way to enable drug
administration via the oral cavity. Polymeric film formulations containing chitosan, sodium …

Quality by design approach in the formulation of glibenclamide mucoadhesive buccal films

SS Shaikh, A Barrawaz - Analytical Chemistry Letters, 2021 - Taylor & Francis
Glibenclamide, an oral hypoglycemic BCS class II drug that gets completely metabolized in
the liver, serves as a suitable candidate for buccal drug delivery. The study aims to formulate …

Buccal films: an assessment of protuberant features, manufacturing contemplations, formulation techniques & characterization strictures

S Faheem, H Hameed, M Zaman… - … Journal of Polymeric …, 2024 - Taylor & Francis
The delivery via buccal route of small molecules as well as large molecules has been a
catching administration route and it was extensively studied over the last few periods. Such …

Investigation of surface properties and free volumes of chitosan-based buccal mucoadhesive drug delivery films containing ascorbic acid

K Kristó, S Módra, V Hornok, K Süvegh, K Ludasi… - Pharmaceutics, 2022 - mdpi.com
Nowadays, the buccal administration of mucoadhesive films is very promising. Our aim was
to prepare ascorbic acid-containing chitosan films to study the properties and structures …

[PDF][PDF] Formulation of mucoadhesive buccal films using pregelatinized cassava starch phthalate as a film-forming polymer

S Surini, F Gotalia, KSS Putri - Int J Appl Pharm, 2018 - academia.edu
Objective: This study aimed to compare the characteristics of four buccal films formulated
with phthalylated cassava starch and their drug delivery potentials. Methods: An alternative …