ZEB1: New advances in fibrosis and cancer

L Cheng, MY Zhou, YJ Gu, L Chen, Y Wang - Molecular and Cellular …, 2021 - Springer
Zinc finger E-box binding homeobox 1 (ZEB1) is an important transcription factor in epithelial
mesenchymal transition (EMT) which participates in the numerous life processes, such as …

The crucial role of ZEB2: from development to epithelial‐to‐mesenchymal transition and cancer complexity

M Fardi, M Alivand, B Baradaran… - Journal of cellular …, 2019 - Wiley Online Library
Zinc finger E‐box binding homeobox 2 (ZEB2) is a DNA‐binding transcription factor, which
is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved …

Regulation of ZEB1 function and molecular associations in tumor progression and metastasis

M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …

Clinicopathological significance of ZEB1 protein in patients with hepatocellular carcinoma

YM Zhou, L Cao, B Li, RX Zhang, CJ Sui, ZF Yin… - Annals of surgical …, 2012 - Springer
Background ZEB1, a member of the ZFH family of proteins (zinc-finger E-box binding
homeobox), plays a central role in epithelial–mesenchymal transition (EMT) during …

Prognostic value of ZEB-1 in solid tumors: a meta-analysis

B Chen, B Chen, Z Zhu, W Ye, J Zeng, G Liu, S Wang… - BMC cancer, 2019 - Springer
Background Zinc-finger E-box binding homeobox 1 (ZEB-1) plays crucial roles in epithelial-
to-mesenchymal transition during tumor carcinogenesis. Published studies have examined …

Post-translational modification of ZEB family members in cancer progression

MK Park, H Lee, CH Lee - International Journal of Molecular Sciences, 2022 - mdpi.com
Post-translational modification (PTM), the essential regulatory mechanisms of proteins, play
essential roles in physiological and pathological processes. In addition, PTM functions in …

[HTML][HTML] High expression of ZEB1 correlates with liver metastasis and poor prognosis in colorectal cancer

GJ Zhang, T Zhou, HP Tian, ZL Liu… - Oncology …, 2013 - spandidos-publications.com
Zinc finger E-box binding homeobox 1 (ZEB1) has been shown to promote invasion and
metastasis in several types of human cancer and to have a prognostic role in certain …

[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications

Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Highly expressed Zinc-finger E-box binding protein 1 (ZEB1) is significantly associated with
the malignancy of various cancers. Signal transduction and activation of ZEB1 play …

[HTML][HTML] ZEB2 promotes tumor metastasis and correlates with poor prognosis of human colorectal cancer

MZ Li, JJ Wang, SB Yang, WF Li, LB Xiao… - American journal of …, 2017 - ncbi.nlm.nih.gov
Colorectal cancer remains the most common cause of cancer-related deaths worldwide and
it continues to lack an effective treatment. Here, we found that zinc finger E-box binding …

[HTML][HTML] ZEB1 promotes tumorigenesis and metastasis in hepatocellular carcinoma by regulating the expression of vimentin

Y Qin, J Yu, M Zhang, F Qin… - Molecular Medicine …, 2019 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and its
prognosis remains poor. Epithelial‑to‑mesenchymal transition (EMT)‑induced markers have …