Direct visualization of serotonin1D receptors in the human brain using a new iodinated radioligand

JM Palacios, C Waeber, AT Bruinvels, D Hoyer - Molecular brain research, 1992 - Elsevier
The development of the new ligand serotonin-5-O-carboxymethyl-glycyl [125 I] tyrosinamide
(abbreviated [125 I] GTI) allows for the direct visualization of serotonin 1B and serotonin 1D …

A comparative autoradiographic study of 5-HT1D binding sites in human and guinea-pig brain using different radioligands

AT Bruinvels, B Landwehrmeyer, A Probst… - Molecular brain …, 1994 - Elsevier
Quantitative receptor autoradiography was used to examine the 5-hydroxytryptamine (5-HT,
serotonin) binding sites labelled with serotonin-5-O-carboxymethyl-glycyl-[125 I] …

Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain

AT Bruinvels, JM Palacios, D Hoyer - Naunyn-Schmiedeberg's archives of …, 1993 - Springer
The regional distribution and the pharmacology of the binding sites labelled with the novel 5-
hydroxytryptamine (serotonin) 5-HT 1B/1D selective radioligand serotonin-O-carboxy-methyl …

Visualization of a novel serotonin recognition site (5-HT1D) in the human brain by autoradiography

C Waeber, MM Dietl, D Hoyer, A Probst, JM Palacios - Neuroscience letters, 1988 - Elsevier
The localization of a novel serotonin (5-hydroxytryptamine, 5-HT) recognition site named 5-
HT 1D was studied by autoradiography in human postmortem brain material. Serotonin-1 …

“5-HT1R” or 5-HT1D sites? Evidence for 5-HT 1D binding sites in rabbit brain

D Hoyer, H Lery, C Waeber, AT Bruinvels… - Naunyn-Schmiedeberg's …, 1992 - Springer
Radioligand binding studies were performed in membranes of rabbit whole brain and
striatum using the novel iodinated radioligand for 5-hydroxytryptamine 5-HT 1B and 5-HT 1D …

Biochemical and Pharmacological Characterization of Serotonin‐O‐Carboxymethylglycyl [125I] Iodotyrosinamide5 a New Radioiodinated Probe for 5‐HT1B and 5 …

P Boulenguez, L Segu, J Chauveau… - Journal of …, 1992 - Wiley Online Library
There is a lack of radioactive probes, particularly radioiodinated probes, for the direct
labeling of serotonin‐1B (5‐HT1B) and serotonin‐ID (5‐HT1D) binding sites. Serotonin‐0 …

5-HT1D binding sites in various species: similar pharmacological profile in dog, monkey, calf, guinea-pig and human brain membranes

AT Bruinvels, H Lery, J Nozulak, JM Palacios… - Naunyn-Schmiedeberg's …, 1992 - Springer
Radioligand binding studies were performed in membranes of calf caudate, guinea-pig
cortex, dog caudate and whole brain, monkey caudate and whole brain, and human caudate …

Synthesis and pharmacological study of radioiodinated serotonin derivative specific of 5-HT1B and 5-HT1D binding sites of the central nervous system

L Segu, J Chauveau, P Boulenguez… - Comptes Rendus de …, 1991 - europepmc.org
We describe here the synthesis of a new serotonin conjugate, S-CM-GTNH2, and its
radioiodinated derivative. Quantitative autoradiographic studies on rat and guinea pig brain …

Radiosynthesis of a new radioiodinated ligand for serotonin‐5HT2‐receptors, a promising tracer for γ‐emission tomography

J Mertens, D Terriere, V Sipido… - Journal of Labelled …, 1994 - Wiley Online Library
Amino‐N‐[1‐[3‐(4‐fluorophenoxy) propyl]‐4‐methyl‐4‐piperidinyl]‐2‐methoxy‐benzamide,
a compound with high affinity for 5HT2‐receptors, was radioiodinated on the 2‐position of …

Serotonin-5-O-carboxymethyl-glycyl [125I] tyrosinamide labels the 5-HT1Dβ receptor subtype in human cortex

MS Beer, DN Middlemiss - European journal of pharmacology, 1993 - Elsevier
This study, carried out in human cerebral cortical membranes, confirms previous findings in
human substantia nigra that serotonin-5-O-carboxymethyl-glycyl [125 I] tyrosinamide ([125 I] …