Toll‐like receptors (TLRs) and other pattern‐recognition receptors (PRRs) of the innate
immune system form functional receptor complexes that recognize and respond to pathogen …

The lipopolysaccharide (LPS) and fimbriae of Porphyromonas gingivalis play important roles
in periodontal inflammation and pathogenesis. We investigated fimbriae and LPS from …

Humans develop periodontitis in response to challenge by microbial dental plaque.
Inflammation begins after perturbation of gingival epithelial cells by subgingival bacteria …

The oral pathogen Porphyromonas gingivalis, as well as its purified fimbriae, are known to
activate TLR2 and induce proinflammatory and proadhesive effects. The TLR2 …

The adherence of Porphyromonas gingivalis to host cells is likely a prerequisite step in the
pathogenesis of P. gingivalis-induced periodontal disease. P. gingivalis binds to and …

In monocytes, the fimbriae of the oral pathogen Porphyromonas gingivalis activate cross talk
signaling from Toll-like receptor 2 (TLR2) to the β2 integrin CD11b/CD18, leading to the …

To characterize the roles of Porphyromonas gingivalis and its components in disease
processes, we investigated the cytokine profiles induced by live P. gingivalis, its …

Introduction 3. Epidemiological Associations Of Infection With Systemic Diseases 3.1.
Infectious Agents And Association With Atherosclerosis 3.2. Periodontal Disease And P …

Emerging data on the consequences of the interactions between invasive oral bacteria and
host cells have provided new insights into the pathogenesis of periodontal disease. Indeed …

Porphyromonas gingivalis, a keystone oral pathogen implicated in development and
progression of periodontitis, may also contribute to the pathogenicity of diseases such as …