Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster
Modulation of reactive oxygen species (ROS) plays a key role in signal transduction
pathways. Selenoproteins act controlling the redox balance of the cell. We have studied how …
pathways. Selenoproteins act controlling the redox balance of the cell. We have studied how …
The {\it Drosophila}{\it selenophosphate synthetase (selD)} gene is required for development and cell proliferation
To study the function of selenoproteins in development and growth we have used a lethal
mutation ({\it selD [TeX:]^{\it ptuf}}) of the {\it Drosophila} homologous selenophosphate …
mutation ({\it selD [TeX:]^{\it ptuf}}) of the {\it Drosophila} homologous selenophosphate …
Halving the selenophosphate synthetase gene dose confers hypersensitivity to oxidative stress in Drosophila melanogaster
M Morey, F Serras, M Corominas - FEBS letters, 2003 - Wiley Online Library
Several lines of evidence indicate that selenoproteins mainly act as cellular antioxidants.
Here, we test this idea comparing the sensitivity to oxidative stress (paraquat and hydrogen …
Here, we test this idea comparing the sensitivity to oxidative stress (paraquat and hydrogen …
Antioxidant function of a novel selenoprotein in Drosophila melanogaster
N Morozova, EP Forry, E Shahid, AM Zavacki… - Genes to …, 2003 - Wiley Online Library
Background: Insects appear to have diverged from both higher and lower organisms in their
defense mechanisms against oxidative damage. They do not encode glutathione …
defense mechanisms against oxidative damage. They do not encode glutathione …
DIAP1 suppresses ROS-induced apoptosis caused by impairment of the selD/sps1 homolog in Drosophila
M Morey, M Corominas, F Serras - Journal of cell science, 2003 - journals.biologists.com
The cellular antioxidant defense systems neutralize the cytotoxic by-products referred to as
reactive oxygen species (ROS). Among them, selenoproteins have important antioxidant …
reactive oxygen species (ROS). Among them, selenoproteins have important antioxidant …
Disruption of selenoprotein biosynthesis affects cell proliferation in the imaginal discs and brain of Drosophila melanogaster
B Alsina, M Corominas, MJ Berry… - Journal of Cell …, 1999 - journals.biologists.com
The patufet gene encodes the Drosophila melanogaster homologue of selenophosphate
synthetase, an enzyme required for selenoprotein synthesis, and appears to have a role in …
synthetase, an enzyme required for selenoprotein synthesis, and appears to have a role in …
Conserved selenoprotein synthesis is not critical for oxidative stress defence and the lifespan of Drosophila
Selenoprotein synthesis is conserved from bacteria to man. It involves the differential
decoding of the UGA stop codon as selenocysteine. The proteomes of both prokaryotes and …
decoding of the UGA stop codon as selenocysteine. The proteomes of both prokaryotes and …
Selenoprotein T is a novel OST subunit that regulates UPR signaling and hormone secretion
A Hamieh, D Cartier, H Abid, A Calas, C Burel… - EMBO …, 2017 - embopress.org
Selenoprotein T (SelT) is a recently characterized thioredoxin‐like protein whose expression
is very high during development, but is confined to endocrine tissues in adulthood where its …
is very high during development, but is confined to endocrine tissues in adulthood where its …
Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor
SB Ben, QY Wang, L Xia, JZ Xia, J Cui, J Wang… - Biochemistry …, 2011 - Springer
Abstract dSelK (G-rich), a homolog of human and mouse SelK, is one of three
selenoproteins in Drosophila melanogaster. It is the only trans-membrane selenoprotein in …
selenoproteins in Drosophila melanogaster. It is the only trans-membrane selenoprotein in …
[HTML][HTML] Analyses of fruit flies that do not express selenoproteins or express the mouse selenoprotein, methionine sulfoxide reductase B1, reveal a role of …
VA Shchedrina, H Kabil, G Vorbruggen, BC Lee… - Journal of biological …, 2011 - ASBMB
Selenoproteins are essential in vertebrates because of their crucial role in cellular redox
homeostasis, but some invertebrates that lack selenoproteins have recently been identified …
homeostasis, but some invertebrates that lack selenoproteins have recently been identified …
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