The present study investigates the molecular apoptotic pathway in germ cells following
acute ischemia of the rat testis. Rats were subjected to ischemia-inducing torsion and testes …

Programmed cell death is an important regulatory event in spermatogenesis. However, the
molecular events governing apoptosis have not been characterized. Using the Leydig cell …

Testis torsion-induced aspermatogenesis is not necessarily due to permanent loss of blood
flow nor to dysfunctional Leydig cells or Sertoli cells. This investigation was undertaken to …

Germ cell apoptosis is very common during various stages of mammalian testicular
development. However, our understanding of the mechanisms underlying male germ cell …

Apoptosis of germ cells is very common in normal and injured mammalian testes. The aim of
this study was to examine the possible involvement of the Fas and Fas ligand (FasL) system …

This study investigates the role of neutrophils in ischemia-induced aspermatogenesis in the
mouse. Previous studies in the rat have demonstrated that ischemia-inducing testicular …

Loss of germ cells is very common during various stages of mammalian spermatogenesis.
Although cell death, particularly apoptosis, has been implicated, our understanding of the …

Ischemia-reperfusion (IR) of the testis results in germ-cell-specific apoptosis (GCA) and a
reduction in daily sperm production. This has been correlated with and is dependent upon …

A growing body of evidence demonstrates that germ cell death both spontaneous (during
normal spermatogenesis) and that induced by suppression of hormonal support or …

Testicular torsion requires emergent release of the twisted spermatic cord.
Ischemia/reperfusion (I/R) plays an important role in its pathogenesis, and recent data …