[PDF][PDF] Hormonal and genetic control of germ cell apoptosis in the testis

APS Hikim, RS Swerdloff - Rev Reprod, 1999 - academia.edu
Programmed cell death is an evolutionarily conserved cell death process that plays a major
role during normal development and homeostasis. In many cases, the ordered execution of …

Caspase-3 and caspase-activated deoxyribonuclease are associated with testicular germ cell apoptosis resulting from reduced intratesticular testosterone

JM Kim, SR Ghosh, ACP Weil, BR Zirkin - Endocrinology, 2001 - academic.oup.com
The purpose of the present study was to examine the possible involvement of caspase-3
and caspase-activated deoxyribonuclease in rat testicular germ cell apoptosis resulting from …

Germ cell apoptosis and expression of Bcl-2 and Bax in porcine testis under normal and heat stress conditions

X Fan, H Xi, Z Zhang, Y Liang, Q Li, J He - Acta histochemica, 2017 - Elsevier
The aim of this study was to examine whether an elevated ambient temperature (37–40° C)
had an effect on the apoptosis of germ cells and the expression of Bcl-2 and Bax in porcine …

Apoptosis and mitosis in gonocytes of the rat testis during foetal and neonatal development

B Boulogne, R Olaso, C Levacher… - … journal of andrology, 1999 - Wiley Online Library
This study was undertaken to determine the extent of apoptosis and mitosis in the various
testicular cell types throughout rat development from foetal day 14.5 to postnatal days 9–10 …

Inhibition of testicular germ cell apoptosis and differentiation in mice misexpressing Bcl-2 in spermatogonia

T Furuchi, K Masuko, Y Nishimune, M Obinata… - …, 1996 - journals.biologists.com
During normal spermatogenesis, more than half of the germ cells undergo apoptosis, but the
physiological significance and molecular mechanisms of this programmed cell death are …

[HTML][HTML] Medical perspective in testicular ischemia‑reperfusion injury

S Arena, R Iacona, P Antonuccio… - Experimental and …, 2017 - spandidos-publications.com
Testicular torsion or torsion of the spermatic cord is one of the most serious urological
conditions. It causes testicular injury, which potentially leads to male subfertility. The turning …

Erythropoietin and sildenafil protect against ischemia/reperfusion injury following testicular torsion in adult rats

ID Kostakis, N Zavras… - Experimental and …, 2017 - spandidos-publications.com
Testicular torsion/detorsion causes severe tissue damage due to ischemia/reperfusion
injury. The present study investigated the protective effect of erythropoietin and sildenafil …

The Fas system is a key regulator of germ cell apoptosis in the testis

J Lee, JH Richburg, SC Younkin… - Endocrinology, 1997 - academic.oup.com
Apoptosis occurs in the testis as an important physiological mechanism to limit the number
of germ cells in the seminiferous epithelium. Sertoli cells, which tightly regulate germ cell …

Role of caspase 2 in apoptotic signaling in primate and murine germ cells

C Johnson, Y Jia, C Wang, YH Lue… - Biology of …, 2008 - academic.oup.com
This study investigates the role of caspase 2 in apoptotic signaling of nonhuman primate
male germ cells triggered by mild testicular hyperthermia, testosterone (Te) implants, or by …

[HTML][HTML] The Fas system may have a role in male reproduction

C Celik-Ozenci, Z Sahin, I Ustunel, G Akkoyunlu… - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: To assess what the distributions of Fas system proteins are in normal rat
testicular tissue; to assess whether there is a change in these distributions and in expression …