The purpose of this study was to determine whether apoptotic cell death of mouse testicular
germ cells varies with increased age, or with exposure to an acute systemic oxidative stress …

The major objectives of the present study were to document the temporal and stage-specific
acceleration of germ cell apoptosis in adult rats after selective suppression of pituitary …

Testicular apoptosis is activated by stress, but it is not clear which signaling pathway is
activated in response to stress. The aim of this study was to investigate whether intrinsic …

In mice, the Fas/Fas ligand (FasL) system has been shown to be involved in germ cell
apoptosis. In the present study we evaluated the expression of Fas and Fas ligand (FasL) in …

The detrimental effects of estrogen on testicular function provide a conceptual basis to
examine the speculative link between increased exposure to estrogens and spermatogenic …

Although it is established that in utero exposure to antiandrogenic compounds such as
flutamide induces hypospermatogenesis in adult male rat offspring, the cellular and …

The number and type of testicular germ cells undergoing apoptosis in different age groups of
mice (from 7 to 360 days of age) was determined and compared in age-matched wild type …

ABSTRACT The Fas/FasL signaling pathway is one of the major pathways that regulate
apoptosis. Increasing studies have shown that the activation of the Fas/FasL signaling …

OBJECTIVE: To investigate the protective effect of honokiol, a phytochemical used in
traditional medicine, on testicular injury after torsion/detorsion (T/D) in a rat model. Testicular …

Induction of cryptorchidism in the mouse causes infertility due to disruption of
spermatogenesis including reduction of germ cells; however, the cellular mechanism …