Anti-obesity effect of chitosan oligosaccharide capsules (COSCs) in obese rats by ameliorating leptin resistance and adipogenesis

H Pan, C Fu, L Huang, Y Jiang, X Deng, J Guo, Z Su - Marine drugs, 2018 - mdpi.com
Obesity is a global disease that causes many metabolic disorders. However, effective agents
for the prevention or treatment of obesity remain limited. This study investigated the anti …

Anti-obese effect of glucosamine and chitosan oligosaccharide in high-fat diet-induced obese rats

L Huang, J Chen, P Cao, H Pan, C Ding, T Xiao… - Marine Drugs, 2015 - mdpi.com
Objective: This study is to evaluate the anti-obese effects of glucosamine (GLC) and
chitosan oligosaccharide (COS) on high-fat diet-induced obese rats. Methods: The rats were …

Chitosan oligosaccharide ameliorated obesity by reducing endoplasmic reticulum stress in diet-induced obese rats

X Deng, Z Ye, H Cao, Y Bai, Q Che, J Guo, Z Su - Food & function, 2020 - pubs.rsc.org
Objective: This study aimed to determine whether chitosan oligosaccharide (COST)
improves overweight by reducing endoplasmic reticulum (ER) stress in the liver and liver …

Anti-obesity effect and mechanism of chitooligosaccharides were revealed based on lipidomics in diet-induced obese mice

M Zhou, J Huang, J Zhou, C Zhi, Y Bai, Q Che, H Cao… - Molecules, 2023 - mdpi.com
Chitooligosaccharide (COS) is a natural product from the ocean, and while many studies
have reported its important role in metabolic diseases, no study has systematically …

Multi-functional roles of chitosan as a potential protective agent against obesity

AM Walsh, T Sweeney, B Bahar, JV O'Doherty - PLOS one, 2013 - journals.plos.org
Chitosan, a natural polysaccharide comprising copolymers of glucosamine and N-
acetylglucosamine, has been shown to have anti-obesity properties. Two experiments (Exp …

Hypolipidemic effects of chitosan and its derivatives in hyperlipidemic rats induced by a high-fat diet

H Pan, Q Yang, G Huang, C Ding, P Cao… - Food & nutrition …, 2016 - Taylor & Francis
Background Hyperlipidemia (HLP) is the primary risk factor of cardiovascular disease (CVD).
Various factors, including genetics, physical inactivity, and daily nutritional habits, affect the …

Antiobese effects of capsaicin–chitosan microsphere (CCMS) in obese rats induced by high fat diet

S Tan, B Gao, Y Tao, J Guo, Z Su - Journal of agricultural and food …, 2014 - ACS Publications
Chitosan (CTS) and capsaicin (CAP) are two kinds of effective ingredients for antiobesity,
which are extracted from crab shells and Capsicum annuum. However, the strong taste of …

Chitosan oligosaccharides improve glucolipid metabolism disorder in liver by suppression of obesity-related inflammation and restoration of peroxisome proliferator …

Y Bai, J Zheng, X Yuan, S Jiao, C Feng, Y Du, H Liu… - Marine Drugs, 2018 - mdpi.com
Chitosan oligosaccharides (COS) display various biological activities. In this study, we
aimed to explore the preventive effects of COS on glucolipid metabolism disorder using …

Functional comparison of high and low molecular weight chitosan on lipid metabolism and signals in high-fat diet-fed rats

SH Liu, CY Chiu, CM Shi, MT Chiang - Marine Drugs, 2018 - mdpi.com
The present study examined and compared the effects of low-and high-molecular weight
(MW) chitosan, a nutraceutical, on lipid metabolism in the intestine and liver of high-fat (HF) …

Effects and mechanisms of chitosan and chitosanoligosaccharide on hepatic lipogenesis and lipid peroxidation, adipose lipolysis, and intestinal lipid absorption in rats …

SH Liu, RY Chen, MT Chiang - International journal of molecular sciences, 2021 - mdpi.com
Chitosan and its derivative, chitosan oligosaccharide (CO), possess hypolipidemic and anti-
obesity effects. However, it is still unclear if the mechanisms are different or similar between …