OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Reactive oxygen species in the mammalian pre-implantation embryo

JC Deluao, Y Winstanley, RL Robker… - …, 2022 - rep.bioscientifica.com
In brief Reactive oxygen species are generated throughout the pre-implantation period and
are necessary for normal embryo formation. However, at pathological levels, they result in …

Reactive oxygen species in reproduction: harmful, essential or both?

M Jamil, H Debbarh, S Aboulmaouahib, OA Filali… - Zygote, 2020 - cambridge.org
The process of embryonic development is crucial and radically influences preimplantation
embryo competence. It involves oocyte maturation, fertilization, cell division and blastulation …

Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings

P Guerin, S El Mouatassim… - Human reproduction …, 2001 - academic.oup.com
Oxidative stress is involved in the aetiology of defective embryo development. Reactive
oxygen species (ROS) may originate from embryo metabolism and/or embryo surroundings …

Oxidative Stress in Oocytes and Embryo Development: Implications for In Vitro Systems

J Lin, L Wang - Antioxidants & Redox Signaling, 2021 - liebertpub.com
Significance: To improve the outcomes of in vitro culture of human oocytes and embryos, the
dynamic balance and roles of reactive oxygen species (ROS) in folliculogenesis and embryo …

The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes

KH Al-Gubory, PA Fowler, C Garrel - … journal of biochemistry & cell biology, 2010 - Elsevier
Reactive oxygen species (ROS) are generated as by-products of aerobic respiration and
metabolism. Mammalian cells have evolved a variety of enzymatic mechanisms to control …

Redox Regulation and Oxidative Stress in Mammalian Oocytes and Embryos Developed In Vivo and In Vitro

MLM Hardy, ML Day, MB Morris - International Journal of Environmental …, 2021 - mdpi.com
Oocytes and preimplantation embryos require careful regulation of the redox environment
for optimal development both in vivo and in vitro. Reactive oxygen species (ROS) are …

Reactive oxygen species in the reproductive system: sources and physiological roles

A Das, S Roychoudhury - Oxidative Stress and Toxicity in Reproductive …, 2022 - Springer
Reactive oxygen species (ROS) are oxygen-containing molecules which are reactive in
nature and are capable of independent existence in the body. ROS comprise mostly of free …

Antioxidants and reactive oxygen species in human fertility

CT Taylor - Environmental toxicology and pharmacology, 2001 - Elsevier
The cellular components of the human reproductive system are as vulnerable as other cells
to the potential detrimental effects of reactive oxygen species (ROS). Antioxidant protection …

Oxidative stress and assisted reproduction: a comprehensive review of its pathophysiological role and strategies for optimizing embryo culture environment

A Agarwal, I Maldonado Rosas, C Anagnostopoulou… - Antioxidants, 2022 - mdpi.com
Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and
antioxidants has been established as an important factor that can negatively affect the …

Oxygen, early embryonic metabolism and free radical-mediated embryopathies

GJ Burton, J Hempstock, E Jauniaux - Reproductive biomedicine online, 2003 - Elsevier
Free radicals, once the preserve of chemists, are now recognized as playing a central role in
many biological systems. They are formed as an inevitable by-product of aerobic respiration …