In this paper, we describe the synthesis of the 3′-3′-linked oligonucleotides connected
with pentaerythritol composed of asymmetrical sequences. Stability of the triplexes between …

This Letter describes the synthesis and properties of double-stranded antisense
oligonucleotides connected with a pentaerythritol linker. We found that double-stranded …

Cyclic oligonucleotides carrying an oligopurine Watson–Crick sequence linked to the
corresponding (G, A)‐and (G, T)‐antiparallel strands were prepared by nonenzymatic …

In this paper, we describe the synthesis of the 3 '-3 '-linked TFOs that can form the
antiparallel triplexes with the duplex DNA target by reverse Hoogsteen hydrogen bonds …

We present our studies on the ability of several different nucleotide analogs as triplex-
forming oligonucleotides. The modifications tested include 4′-C-hydroxymethyl, LNA, 2 …

Synthesis of 3 '-3 '-linked oligonucleotides branched by a pentaerythritol linker is described.
The branched oligonucleotides were synthesized on a DNA/RNA synthesizer using a …

For development of ideal antisense and antigene molecules, various chemical modifications
of oligonucleotides have been studied. However, despite their importance, there is only …

A new concept is presented to design and synthesize modified oligonucleotides in order to
extend the range of double-helical DNA sequences that can be recognized by …

Novel nucleoside analogues containing 2′-deoxyinosine and aromatic rings, which are
connected by short linker groups, were synthesized and incorporated into …

The N-acetyl derivatives 1a and 2a of the aminotriazole and aminoimidazole 2′-
deoxynucleosides 1 and 2 were synthesized as potential substitutes of protonated 2 …