PIWI‐interacting RNAs are aberrantly expressed and may serve as novel biomarkers for diagnosis of lung adenocarcinoma

J Li, N Wang, F Zhang, S Jin, Y Dong, X Dong… - Thoracic …, 2021 - Wiley Online Library
Background Lung adenocarcinoma (LUAD) is the main subtype of primary lung cancer and
is a leading cause of cancer‐related death worldwide. PIWI‐interacting RNAs (piRNAs) are …

Serum-derived piR-hsa-164586 of extracellular vesicles as a novel biomarker for early diagnosis of non-small cell lung cancer

Y Li, Y Dong, S Zhao, J Gao, X Hao, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung cancer (NSCLC) is a major cause of death in those with malignant
tumors. To achieve the early diagnosis of NSCLC, we investigated serum-derived Piwi …

[HTML][HTML] PIWI-interacting RNAs piR-13643 and piR-21238 are promising diagnostic biomarkers of papillary thyroid carcinoma

Z Chang, G Ji, R Huang, H Chen, Y Gao… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Emerging studies demonstrate that PIWI-interacting RNAs (piRNAs) participate in the
development of cancers. 75 pairs of papillary thyroid carcinoma (PTC) samples and 31 …

Circulating PIWI-interacting RNAs piR-5937 and piR-28876 are promising diagnostic biomarkers of colon cancer

P Vychytilova-Faltejskova, K Stitkovcova… - … Biomarkers & Prevention, 2018 - AACR
Background: The early detection of colon cancer is one of the main prerequisites for
successful treatment and mortality reduction. Circulating PIWI-interacting RNAs (piRNA) …

Serum PIWI-interacting RNAs piR-020619 and piR-020450 are promising novel biomarkers for early detection of colorectal cancer

Z Wang, H Yang, D Ma, Y Mu, X Tan, Q Hao… - … Biomarkers & Prevention, 2020 - AACR
Background: Early diagnosis can significantly reduce colorectal cancer deaths. We sought to
identify serum PIWI-interacting RNAs (piRNAs) that could serve as sensitive and specific …

Piwi-interacting RNAs (piRNAs) are dysregulated in renal cell carcinoma and associated with tumor metastasis and cancer-specific survival

Y Li, X Wu, H Gao, JM Jin, AX Li, YS Kim, SK Pal… - Molecular …, 2015 - Springer
Piwi-interacting RNAs (piRNAs) are a distinct group of small noncoding RNAs (sncRNAs)
that silence transposable genetic elements to protect genome integrity. Because of their …

[HTML][HTML] PIWI-interacting RNA-54265 is oncogenic and a potential therapeutic target in colorectal adenocarcinoma

D Mai, P Ding, L Tan, J Zhang, Z Pan, R Bai, C Li… - Theranostics, 2018 - ncbi.nlm.nih.gov
Abstract Although PIWI-interacting RNAs (piRNAs) have recently been linked to human
diseases, their roles and functions in malignancies remain unclear. This study aimed to …

Global analyses of expressed piwi-interacting RNAs in gastric cancer

T Vinasco-Sandoval, FC Moreira, A F. Vidal… - International Journal of …, 2020 - mdpi.com
Gastric cancer (GC) represents a notable amount of morbidity and mortality worldwide.
Understanding the molecular basis of CG will offer insight into its pathogenesis in an attempt …

Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer

W Weng, N Liu, Y Toiyama, M Kusunoki, T Nagasaka… - Molecular cancer, 2018 - Springer
Background Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may be
important epigenetic regulators of gene expression in human cancers; however, their …

Identification of piRNA targets in urinary extracellular vesicles for the diagnosis of prostate cancer

Q Peng, PKF Chiu, CYP Wong, CKL Cheng, JYC Teoh… - Diagnostics, 2021 - mdpi.com
Emerging studies demonstrate that PIWI-interacting RNAs (piRNAs) are associated with
various human cancers. This study aimed to evaluate the urinary extracellular vesicles (EVs) …