[HTML][HTML] Small RNA Profiling of piRNAs in Colorectal Cancer Identifies Consistent Overexpression of piR-24000 That Correlates Clinically with an Aggressive Disease …

DN Iyer, TMH Wan, JHW Man, RWY Sin, X Li, OSH Lo… - Cancers, 2020 - mdpi.com
Piwi-interacting RNAs (piRNAs) represent a novel class of small non-coding RNAs
(ncRNAs) that have been shown to have a deregulated expression in several cancers …

[HTML][HTML] PIWI-interacting RNAs in cancer: Biogenesis, function, and clinical significance

J Yao, M Xie, X Ma, J Song, Y Wang, X Xue - Frontiers in Oncology, 2022 - frontiersin.org
PIWI-interacting RNAs (piRNAs) are a less-studied class of small non-coding RNAs
approximately 24–31 nucleotides in length. They express in germline and somatic cells and …

[HTML][HTML] Transcriptome analysis identifies piwi-interacting RNAs as prognostic markers for recurrence of prostate cancer

Y Zuo, Y Liang, J Zhang, Y Hao, M Li, Z Wen… - Frontiers in …, 2019 - frontiersin.org
Prostate cancer remains the second leading cause of male cancer death, and there is an
unmet need for biomarkers to identify patients with such aggressive disease. Piwi-inteacting …

[HTML][HTML] The biogenesis and biological function of PIWI-interacting RNA in cancer

S Chen, S Ben, J Xin, S Li, R Zheng, H Wang… - Journal of hematology & …, 2021 - Springer
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …

[HTML][HTML] piR-651 and its function in 95-D lung cancer cells

J Yao, YW Wang, BB Fang, SJ Zhang… - Biomedical …, 2016 - spandidos-publications.com
PIWI-associated RNAs (piRNAs or piRs), a new-found class of small non-coding RNAs,
which are mainly expressed in germline cells and partly in somatic lines, have a vital role in …

Mitochondrial PIWI-interacting RNAs are novel biomarkers for clear cell renal cell carcinoma

C Zhao, Y Tolkach, D Schmidt, M Toma… - World Journal of …, 2019 - Springer
Abstract Purpose PIWI-interacting RNAs (piRNAs) have been suggested to serve as
biomarkers in cancer. In this study, we validated the expression profile of two piRNAs …

PIWI interacting RNAs perspectives: a new avenues in future cancer investigations

P Mokarram, M Niknam, M Sadeghdoust… - …, 2021 - Taylor & Francis
As a currently identified small non-coding RNAs (ncRNAs) category, the PIWI-interacting
RNAs (piRNAs) are crucial mediators of cell biology. The human genome comprises over …

[HTML][HTML] Small RNA Sequencing Identifies PIWI-Interacting RNAs Deregulated in Glioblastoma—piR-9491 and piR-12488 Reduce Tumor Cell Colonies In Vitro

M Bartos, F Siegl, A Kopkova, L Radova… - Frontiers in …, 2021 - frontiersin.org
Glioblastoma (GBM) is the most frequently occurring primary malignant brain tumor of
astrocytic origin. To change poor prognosis, it is necessary to deeply understand the …

[HTML][HTML] PIWI-RNAs Small Noncoding RNAs with Smart Functions: Potential Theranostic Applications in Cancer

S Taverna, A Masucci, G Cammarata - Cancers, 2023 - mdpi.com
Simple Summary P-element-induced wimpy testis-interacting RNAs (piRNAs) are a novel
class of small regulatory RNAs that often bind to PIWI proteins. First identified in animal germ …

[HTML][HTML] PIWI‑interacting RNA in cancer: Molecular mechanisms and possible clinical implications

C Yuan, H Qin, M Ponnusamy… - Oncology …, 2021 - spandidos-publications.com
PIWI‑interacting RNA is a class of non‑coding small RNA that is~ 30 nt long and is primarily
found in mammalian germ cells from mice and humans. In cooperation with the members of …