[HTML][HTML] Identification of HSP90 as potential biomarker of biliary atresia using two-dimensional electrophoresis and mass spectrometry

R Dong, P Deng, Y Huang, C Shen, P Xue, S Zheng - PloS one, 2013 - journals.plos.org
Biliary atresia (BA) is a devastating cholestatic liver disease targeting infants. Current
diagnosis depends on surgical exploration of the biliary tree. The aim of the present study …

Identification of serum protein biomarkers in biliary atresia by mass spectrometry and enzyme-linked immunosorbent assay

Z Song, R Dong, Y Fan, S Zheng - Journal of pediatric …, 2012 - journals.lww.com
Objective: There is an urgent need to identify noninvasive and convenient biomarkers for
early diagnosis of biliary atresia (BA). The aim of the present study was to identify potential …

Proteomics defines plasma biomarkers for the early diagnosis of biliary atresia

M Fu, Z Guo, Y Chen, JR Lamb, S Zhong… - Journal of Proteome …, 2024 - ACS Publications
Early diagnosis of biliary atresia (BA) is crucial for improving the chances of survival and
preserving the liver function of pediatric patients with BA. Herein, we performed proteomics …

[HTML][HTML] Discovery of Candidate Stool Biomarker Proteins for Biliary Atresia Using Proteome Analysis by Data-Independent Acquisition Mass Spectrometry

E Watanabe, Y Kawashima, W Suda, T Kakihara… - Proteomes, 2020 - mdpi.com
Biliary atresia (BA) is a destructive inflammatory obliterative cholangiopathy of the neonate
that affects various parts of the bile duct. If early diagnosis followed by Kasai …

Distinct plasma bile acid profiles of biliary atresia and neonatal hepatitis syndrome

K Zhou, J Wang, G Xie, Y Zhou, W Yan… - Journal of proteome …, 2015 - ACS Publications
Biliary atresia (BA) is a severe chronic cholestasis disorder of infants that leads to death if
not treated on time. Neonatal hepatitis syndrome (NHS) is another leading cause of …

Targeted metabolomics reveals birth screening biomarkers for biliary atresia in dried blood spots

Y Xiao, Y Zhou, K Zhou, W Cai - Journal of Proteome Research, 2021 - ACS Publications
Early diagnosis and timely surgical Kasai portoenterostomy greatly improve the survival of
patients with biliary atresia (BA), a neonatal cholestatic disease, which has encouraged …

Metabonomics reveals metabolite changes in biliary atresia infants

K Zhou, G Xie, J Wang, A Zhao, J Liu… - Journal of proteome …, 2015 - ACS Publications
Biliary atresia (BA) is a rare neonatal cholestatic disorder caused by obstruction of extra-and
intra-hepatic bile ducts. If untreated, progressive liver cirrhosis will lead to death within 2 …

Serum markers may distinguish biliary atresia from other forms of neonatal cholestasis

H Wang, JP Malone, PE Gilmore… - Journal of pediatric …, 2010 - journals.lww.com
Background: Biliary atresia (BA) is the most serious liver disease in infants. Diagnosis
currently depends on surgical exploration of the biliary tree. Noninvasive tests that …

[HTML][HTML] Biliary atresia and cholestasis plasma non-targeted metabolomics unravels perturbed metabolic pathways and unveils a diagnostic model for biliary atresia

B Du, K Mu, M Sun, Z Yu, L Li, L Hou, Q Wang, J Sun… - Scientific Reports, 2024 - nature.com
The clinical diagnosis of biliary atresia (BA) poses challenges, particularly in distinguishing it
from cholestasis (CS). Moreover, the prognosis for BA is unfavorable and there is a dearth of …

Recent studies on non-invasive biomarkers useful in biliary atresia–a literature review

A Lew-Tusk, M Pęksa… - Acta Biochimica …, 2023 - abp.ptbioch.edu.pl
The aim of this review is to specify new potential reliable and non-invasive methods for the
diagnosis of biliary atresia (BA) that could shorten the way to diagnose BA, and finally the …